To compare the efficacy and safety of two surgical procedures by evaluating the effectiveness and safety of the former.

Adjuvant or salvage systemic therapy after nephrectomy for intermediate and high-risk clear cell Renal Cell Carcinoma (ccRCC) improve overall survival. However, severe renal impairment represents a relative contraindication to systemic therapy administration. This study aimed to analyze the impact of overweight and obesity at the time of nephrectomy in determining subsequent renal function impairment and limited accessibility to systemic therapy.

Objective To evaluate the efficacy of Ningmitai capsule (NMT), a traditional Chinese medicine, alone or combined with tamsulosin, in promoting residual stone fragment clearance after Ureteroscopic Holmium Laser Lithotripsy (Ho:YAG-URS). Methods In this multicenter, prospective, randomized controlled trial, 222 patients with distal ureteral residual fragments (3.18 ± 1.14 mm) post-Ho:YAG-URS were assigned to three groups: control (no medication), NMT (0.38g × 4 capsules, 3 times/day), or NMT + tamsulosin (0.4 mg/day). Primary outcome was the stone-free rate (SFR) at 4 weeks. Secondary outcomes included stone expulsion rate, stone-free time, and expulsion time. Results At 4 weeks, SFRs were 76.19% (control), 92.21% (NMT; p = 0.023 vs. control), and 98.91% (combination; p < 0.001 vs. control). The combination group achieved significantly shorter stone-free time (6.37 ± 2.25 vs. 15.82 ± 21.62 days, p < 0.0001) and expulsion time (2.27 ± 1.17 vs. 6.64 ± 10.56 days, p < 0.0001) compared to the control group. No drug-related adverse events were reported. Conclusions NMT significantly accelerates residual fragment expulsion post-Ho:YAG-URS, with synergistic effects observed when combined with tamsulosin. This study demonstrates that patients can benefit from Ningmitai capsules alone or combined with tamsulosin, particularly for small fragments where alpha-blockers show limited efficacy.

Arteriosclerosis is common in candidates for kidney transplantation (KT) due to cardiovascular comorbidities and chronic dialysis. Previous studies have demonstrated the prognostic relevance of pelvic calcification on the surgical outcome after KT. The aim of this study is to evaluate the potential of the computed tomography (CT)-based pelvic calcification score (PCS) as a predictive marker of outcome and survival in KT in a comprehensive analysis.

The aim of this study is to explore the role of systemic immune indices (systemic immune inflammation index and systemic inflammatory response index) in the differential diagnosis between chRCC and oncocytoma.

Extended pelvic lymphadenectomy (ePLND) is the gold standard for staging prostate cancer (PCa) in patients at risk of lymph node invasion (LNI), though its oncological benefit remains debated. Indocyanine green-guided PLND (ICG-PLND) has emerged as a less morbid alternative, but its long-term oncological efficacy compared to ePLND is unclear.

Bladder cancer (BC), the most prevalent type of cancer in the urinary system globally, presents a substantial health challenge worldwide. Although the global burden of disease (GBD) study provides valuable insights, thorough analyses of BC are still scarce. This study utilizes the latest GBD dataset to examine the impact of BC, combining current statistics with projections for 2036.

The aim of this study was to evaluate the predictive value of the Node Reporting and Data System (Node-RADS) for lymph node involvement (LNI) in prostate cancer (PCa) using preoperative multiparametric MRI (mpMRI) and to assess its utility in risk stratification.

Introduction Routine systematic prostate biopsy still is recommended beside targeted biopsies, since without, a significant proportion of prostate cancer (PCa) will be missed. Out of the various methods we investigated two in a head-to-head comparison: the volumetric-optimized software supported (VOT) and the conventional cognitive freehand (CFT) ultrasound-guided systematic prostate biopsy. Methods This is a retrospective analysis within a consecutive cohort of men undergoing prostate biopsy between 2014 and 2023. Baseline characteristics, diagnostic performance in detecting PCa with corresponding relative risks have been assessed. Results 573 patients have been included into analysis; 135 in the CFT and 438 in the VOT group. In the CFT-group, 25(18.5%) showed positive with significant PCa(defined as Gleason Score ≥7), in the VOT-group 125(28.5%), respectively. The relative risk for the diagnosis of significant cancer was statistically significant higher in the VOT compared to the CFT group with a relative risk of 1.54 (95% CI from 1.05 to 2.26), whereas the relative risk for insignificant cancer was almost identical. Conclusion Our results showed that VOT has better diagnostic performance than CFT in detecting significant prostate cancer (defined as Gleason Score ≥7). Taking the study limitations into consideration, the corroboration of our results in other cohorts would promote their generalizability.

Baseline renal function plays a crucial role in influencing postoperative functional decline following minimal invasive partial nephrectomy (PN), yet its impact remains inadequately understood. This study aims to elucidate the relationship between baseline renal function and postoperative decline in renal function.

The aim of the study was to evaluate the safety and efficacy of same-day versus next-day urinary catheter removal following ureteroscopic holmium laser lithotripsy (with routine double-J stent placement) in a day-surgery setting.

The aim of the study was to determine the interactive effect of pelvic organ prolapse (POP) on voiding dynamics of female patients with urodynamic stress urinary incontinence (USUI). Free urine flow curve pattern (FUFCP) criterion was implemented to bladder outlet obstruction (BOO) and detrusor underactivity definitions.

Patient education materials (PEMs) play a vital role in ensuring that patients understand their medical conditions and treatment options. In prostate cancer, complex medical terminology can hamper comprehension and informed decision-making. This study evaluates the readability of prostate cancer PEMs to determine if they meet recommended standards for lay audiences.

The aim of the study was to explore whether patients with autosomal dominant polycystic kidney disease (ADPKD) require native nephrectomy prior to kidney transplantation.

The College of American Pathologists (CAP) provides synoptic reporting (SR) histopathological protocols for various malignancies, e.g., for bladder cancer. We investigated whether SR can enhance the quality of histopathological reporting at our institution. Specifically, we examined whether SR supports pathologists in report preparation and whether urologists of varying training levels fully understand the histopathological information in narrative reports (NR).

Sexually transmitted infections (STIs) continue to rise globally, posing a significant health challenge. This study investigated gender-specific differences in symptom reporting of urethritis, healthcare-seeking behavior, and diagnostic pathways among patients in a German urological practice.

Ureteropelvic junction obstruction (UPJO) is a common disease of the urinary system. Laparoscopic pyeloplasty, especially robot-assisted laparoscopic pyeloplasty, has become the primary surgical method for the treatment of UPJO. As YouTube gradually becomes a platform for young doctors to learn surgical techniques, we intend to assess these surgical videos of traditional laparoscopic pyeloplasty and robot-assisted pyeloplasty on YouTube in terms of their educational quality.

The aim of the study was to evaluate the predictive value of Mayo Adhesive Probability (MAP) and the Estimation of Physiologic Ability and Surgical Stress (E-PASS) scores for postoperative complications in laparoscopic total adrenalectomy (LTA) and partial adrenalectomy (LPA).

The aim of the study was to evaluate the efficacy and safety of percutaneous antegrade flexible ureteroscopic lithotripsy (PAFUL) using a tip-bendable suction ureteral access sheath (UAS) for managing middle and lower ureteral stones after failed retrograde ureteroscopy.

The study aimed to compare pain scores during flexible cystoscopy among male patients in different positions: supine position versus lithotomy position.