Psychiatry Investigation

Clinical Characteristics and Personality Traits of Pediatric and Adult Patients With Avoidant/Restrictive Food Intake Disorder and Anorexia Nervosa-Restricting Type
Kim JO, An Z, Kim M and Kim YR
This study investigated the clinical features and personality traits of pediatric and adult patients with avoidant/restrictive food intake disorder (ARFID) and anorexia nervosa-restricting type (RAN) in a Korean hospital cohort, and the distinct characteristics of ARFID in a non-Western sample.
The Mental Health Profile of Borderline Intellectual Functioning: A Systematic Review
Cho M, Ko E, Choi H, Han DG, Kim HJ, Kim B and Park MH
Psychiatric morbidity patterns and associated outcomes among individuals with borderline intellectual functioning (BIF) remain poorly characterized. This systematic review aims to examine mental health outcomes in BIF populations compared to individuals with normal intellectual functioning and those with intellectual disability (ID).
Gaps and Opportunities in Global Mental Health Research: Disparities Across Geographic Regions and Income Levels
Acuña-Rodríguez M, Quintero KFM, Bolaño-Romero MP and Lozada-Martinez ID
Global Burden of Depressive Disorders, 1990-2021, During the COVID-19 Pandemic and Projections to 2050: A Global Burden of Disease Study 2021
Lee E, Jeong J, Hong S, Lee S, Kong J, Lee H and Yon DK
Despite an increase in the depressive disorders burden during the coronavirus disease-2019 (COVID-19) pandemic, research remains insufficient. This study aims to advance the understanding of the global depressive disorders burden, focusing on the COVID-19 pandemic.
Validation of the Korean Version of the Center for Epidemiologic Studies Depression Scale-Revised in Korean Adolescents
Kim JM, Choi KS, Nam JA, Han HW and Yu JC
The Korean version of the Center for Epidemiologic Studies Depression Scale-Revised (K-CESD-R) is widely used in community epidemiology studies to screen depressive symptoms, given its proven reliability in diverse populations. However, it has not yet been validated in Korean adolescents. Therefore, this study validated and standardized the K-CESD-R for use in Korean adolescents.
A Randomized Controlled Trial of Group-Based Acceptance and Commitment Therapy for Major Depressive Disorder
Lee SW, Seo HS, Choi M and Lee SJ
Major depressive disorder (MDD) is a prevalent and debilitating psychiatric condition. This study developed a group-based acceptance and commitment therapy (GACT) program for MDD and conducted a randomized controlled trial to evaluate its effectiveness. The study aims to assess the effects of GACT and identify factors influencing depression recovery in patients with MDD in Korea.
Independent Role of White Matter Hyperintensity Volume and Location in Alzheimer's Disease Risk Beyond Hippocampal Atrophy
Yang HJ, Song JM and Park JH
Increases in white matter hyperintensities (WMH) observed on brain MRI are associated with the onset of Alzheimer's disease (AD) and cognitive decline. Recent hypotheses suggest that the impact of WMH on cognition may differ by their distance from the ventricular surface. This study aimed to investigate the effects of WMH volume and location, classified by distance from the ventricular surface, on cognitive function in individuals with AD.
The Impact of Psychiatric Interventions on Mortality in Patients With Alcohol-Related Diseases
Jeong DH, Ann ME, Kim SM, Kim JH and Lee SK
This study aimed to examine the current status of psychiatric therapy and anti-craving prescriptions for patients with alcohol-related diseases and to evaluate the impact of these treatments on the prognosis of alcohol-related diseases for drawing implications.
Effects of Tablet-Based Cognitive Training in Cognitively Unimpaired Older Adults: A Randomized Controlled Trial
Kim BR, Moon S, Chung S, Jeong JH and Kim GH
This study aimed to evaluate the neurophysiological and cognitive effects of a tablet-based cognitive training program in cognitively unimpaired (CU) older adults, in order to explore its potential as an accessible intervention for promoting cognitive health in aging populations.
Predictive Validity and Cutoff Scores of the Revised Suicide Crisis Inventory in Korean Adults: A One-Year Follow-Up Study
Ma G and You S
This study aimed to examine the predictive validity of the revised Suicide Crisis Inventory (SCI-2) and determine its optimal cutoff score.
Effectiveness of Group Cognitive Behavioral Therapy and the Role of Cognitive Ability in Adult Attention-Deficit/Hyperactivity Disorder
Lee SA, Lee AR, Yoon NH, Kim CB, Bahn GH and Oh M
Attention-deficit/hyperactivity disorder (ADHD) frequently persists into adulthood and leads to significant impairment across multiple domains. Cognitive behavioral therapy (CBT) has been proposed as a promising adjunctive treatment. We aimed to evaluate the effectiveness of a structured group-based CBT program for adults with ADHD and examine whether cognitive ability and treatment adherence moderate treatment response.
The Mediating Roles of Rumination and Resilience in the Association Between Borderline Personality Features and Suicidality in College Students
He Y, Wu S, Yang T, Chen L, Cui X, Zhang Y, Liu J and Luo X
This study investigates the prevalent characteristics of suicidality in college students with borderline personality (BP) features. In addition, it explores the relationship between BP features and suicidality and analyzes related psychological mechanisms.
Esketamine Nasal Spray for Treatment-Resistant Bipolar II Depression: A Case Report
Lin HC, Chang CY, Lin CH, Chiang YC and Chang CH
This case report discusses a 62-year-old male with treatment-resistant bipolar II depression and hypertension. After poor responses to multiple treatments, an add-on esketamine nasal spray (ESK-NS) was introduced in October 2022. Improvement was seen, and the patient's depressive episode was nearly remitted during the maintenance phase. However, recurrence was noted when ESK-NS frequency was reduced to once every 2 months, indicating that the dosing frequency should be adjusted cautiously. The patient experienced common side effects, including dissociation, dizziness, and transient hypertension. Nifedipine was offered when his systolic blood pressure exceeded 160 mm Hg, accompanied by headache or dizziness. Blood pressure monitoring was essential throughout ESK-NS treatment. This report highlights esketamine's potential for bipolar depression treatment and calls for further studies on its cardiovascular effects and proper management.
Optimizing Suicide Risk Prediction in Korea: A Comparison of Model Performance Using Resampling Methods and Machine Learning Algorithms
Lim E, Kim BJ, Cha B, Lee SJ, Choi JW, Kang N, Park S, Seo SH and Lee D
Machine learning (ML) can assist in predicting suicide risk and identifying associated risk factors. Various resampling methods and algorithms must be applied to develop an ML prediction model with better performance. In this study, we developed an optimal Korean suicide prediction model by applying five ML algorithms, unsampled data, and two resampling methods.
Alcohol Drinking and the Associations Between Age and Posttraumatic Stress Disorder: A 2-Year Longitudinal Study
Kim JM, Kim JW, Kang HJ, Jang H, Kim JC, Chun BJ, Lee JY, Kim SW and Shin IS
This study aimed to examine the associations between age group, alcohol drinking status, and the development of posttraumatic stress disorder (PTSD) over a 2-year period in individuals who have sustained physical injuries.
All-Cause Mortality and Bleeding Risks Associated With Serotonin Reuptake Inhibitors in Patients With End-Stage Kidney Disease and Depression: A Nationwide Cohort Study
Lee J, Park M, Shin DH, Park S, Jung YS, Park K, Cambridge CK, Park S, Han BG and Lee JY
The prevalence of depression is high among patients with end stage kidney disease (ESKD). To date, there has been limited investigation into the comparative effects of antidepressant in patients with ESKD. This study aims to explore the association between type of antidepressant, incidence of all-cause death, and hospitalization for major bleeding in patients with ESKD and depression.
Exploring the Relationship Between Depression and Attention-Deficit/Hyperactivity Disorder Symptoms in Children Using Brain Activity Monitoring
Kim J, Hahn SW, Warburton W, Hwang J, Kim M, Lee M, Lee K and Lee YJ
Although depression is a common comorbidity in children with attention-deficit/hyperactivity disorder (ADHD), its neurophysiological relationship according to each symptom has rarely been explored. This study aimed to inform clinical practice by exploring the neurophysiological underpinnings of depression comorbidity in ADHD.
Functioning Level as a Buffer: Longitudinal Associations Between Heart Rate Variability and Post-Traumatic Stress Disorder Risk Over 2 Years
Kim JM, Kang HJ, Kim JW, Jang H, Kim JC, Lee JY, Kim SW and Shin IS
This study examined the modifying effects of functional levels on the associations of the low frequency (LF) and high frequency (HF) components of heart rate variability (HRV) with post-traumatic stress disorder (PTSD) development.
Cognitive and Psychological Characteristics in Young Adults With Major Depressive Disorder and Suicide Attempts
Lee HW, Park SY, Jeong HJ, Lee JY, Yoo SY and Park SM
This study aims to identify the cognitive and psychological characteristics associated with suicide attempts in young adults with major depressive disorder (MDD).
Analysis of Antipsychotic Drug Use Patterns and Safety in Patients With Bipolar Disorder
Cheng L, Chu W, Yang J, Zhao B and Wan T
To investigate the pattern of antipsychotic drug use and safety in patients with bipolar disorder (BD).
Exploration of Stress-Coping Behaviors in Patients With Mood Disorders Using Cluster Analysis
Jeong H, Moon E, Lim H, Kim K, Suh H, Lee YM, Lee BD and Park JM
Stress and coping strategies can influence the onset and recurrence of mood episodes. Assessment and classification of stress-coping behaviors might be necessary for intervention to correct maladaptive coping strategies. This study aimed to explore clinical types of stress-coping behaviors in patients with mood disorders using cluster analysis, and compare clinical characteristics among clusters.
Interleukin-40 and Oxidative Stress in Patients With Generalized Anxiety Disorder
Fedai ÜA, Çetin SB, Koyuncu İ and Akıl Ö
Interleukin (IL)-40 is a recently identified cytokine implicated in inflammatory diseases. Increasing evidence links anxiety disorders to heightened inflammation. This study aimed to investigate IL-40 levels and oxidative stress in patients with generalized anxiety disorder (GAD).
Depression, Anxiety, and Stress in a Burned-Out Oncologist
Randjelovic N, Peulic M, Petronijevic M, Djuric A and Dugalic K
Considering the established intertwined relationships between burnout and other psychiatric disorders, this study aimed to clarify the existing levels of depression, anxiety, stress, emotional exhaustion, depersonalization, and personal accomplishment and their relationship among oncologists-a seemingly professional group at risk for mental health issues development.
Association Between Physical Activity and the Risk of Dementia Among Patients With Depression: A Nationwide Cohort Study
Yook VM, Jung JH, Han K, Kim H and Jeon HJ
This study investigates the impact of changes in physical activity (PA) on the risk of developing dementia in individuals diagnosed with depression, using a large-scale, retrospective national cohort dataset.
Indonesian Validation of the YouTube Addiction Scale Among Young Adults
Ruckwongpatr K, Nurmala I, Muthmainnah M, Salim LA, Nadia A, Devi YP, Hsieh GJ, Lin YC, Pramukti I, Chen CY, Pakpour AH, Griffiths MD and Lin CY
There is an increasing body of evidence suggesting that YouTube addiction may be associated with health issues among individuals in Indonesia. However, there is currently no validated instrument available in the Indonesian language to assess YouTube addiction. The present study represents the inaugural effort to translate and evaluate the psychometric properties of the Indonesian version of the YouTube Addiction Scale (YAS).
Predicting Efficacy of Virtual Reality-Based Stabilization for Individuals With Posttraumatic Stress Symptoms: A Machine Learning Approach
Shin Y, Kim E, Kim K, Kim JS, Kim S and Kim BN
The global impact of respiratory infectious diseases led to significant mental health challenges, highlighting the need for proactive psychological interventions to prepare for future pandemics. In response, virtual reality-based stabilization (VRS) was developed to mitigate posttraumatic stress symptoms (PTSS) and related comorbidities.
Validation of the Korean Version of the Self-Compassion Scale-Short Form Among Young Adults: A Comparison of Factor Structures
Oh D, Na H and Jung YE
Self-compassion plays a crucial role in emotional well-being and positive mental health. Self-Compassion Scale (SCS) can facilitate measurement of psychological distress and positive affect. SCS-Short Form (SCS-SF) offers an economical and efficient means of reducing burden of both respondents and researchers.
The Moderating Effect of Dating Violence Awareness on the Relationship Between Clinginess and Dating Violence
Ann JE and Bae SM
This study examined the moderating effect of dating violence awareness on the relationship between clinginess and dating violence.
Diagnostic Value of Electroencephalography Features and Serum Neurotrophic Factors in Differentiating Attention-Deficit/Hyperactivity Disorder Subtypes
Zhao Q, Wang R, Lin Y, Guo H, Wang Y, Zhang J, Zhang Q and Ji S
Attention-deficit/hyperactivity disorder (ADHD) includes three subtypes: inattentive type (ADHD-I), hyperactive/impulsive type (ADHD-HI), and combined type (ADHD-C). Diagnosis mainly relies on subjective behavioral rating scales, lacking objective biomarkers. Electroencephalography (EEG) and serum neurotrophic factors-brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), glial cell line-derived neurotrophic factor (GDNF), and neurotrophin-3 (NTF3)-may aid subtype differentiation. This study evaluates their combined diagnostic value in children with ADHD.
Association Between Weekend Catch-Up Sleep and Depression: Evidence From the 2017-2018 National Health and Nutrition Examination Survey
Cai W, Lai Z, Huang S, Xiao F, Liu X, Zhao Y and Luo Y
Weekend catch-up sleep (CUS) has been associated with certain health benefits; however, there is a paucity of research regarding the correlation between CUS and depression in adults. This study aimed to investigate the association between weekend CUS and depressive symptoms in a nationally representative adult population.