The aim of this Guideline was to devise a standardized and simplified diagnostic overview of women with urinary urgency and other symptoms indicative of the overactive bladder (OAB) syndrome.

Recurrent miscarriage is a multifactorial condition, with immune dysregulation proposed as a potential contributing factor. This study investigates the causal relationship between immune cell phenotypes and miscarriage risk using Mendelian randomization (MR).

Caring for newborns with life-limiting conditions represents one of the most demanding professional and emotional challenges for healthcare staff, particularly nurses and midwives. The aim of this study was to examine the relationship between empathy levels, professional competence, occupational stress, and psychosomatic symptoms among professionals working in neonatal care settings.

This study aims to explore the efficacy and safety of vaginal natural orifice transluminal endoscopic surgery (vNOTES), laparoscopy, and robot-assisted laparoscopic myomectomy (RALM) for uterine fibroid removal.

The high survival rate of pediatric cancer patients has prompted a growing research focus on the long-term sequelae of cancer treatment. Premature ovarian insufficiency (POI) and infertility, which are the consequences of the gonadotoxic effects of anticancer therapy, have a profound impact on the quality of life of the affected individuals. A rapidly evolving field of oncofertility has emerged in an attempt to establish a structured approach to fertility preservation in oncologic patients. This study presents the practical aspects of fertility preservation strategies, in accordance with the latest guidelines for young female patients undergoing cancer treatment during childhood and adolescence, as well as the experience of the Gdansk Center in harvesting ovarian tissue for cryopreservation.

Pelvic organ prolapse is an extremely important therapeutic problem and affects up to 50% of nulliparous women. Its frequency increases with age parity, and it is more common after menopause. This ailment has a negative impact on many aspects of life, significantly reducing its quality. Nowadays, not only the cure of the problem, but also the improvement of the quality of life and life satisfaction of patients is of great importance for doctors, therefore the assessment of these aspects should also be constantly evaluated. The objective of this study was to determine the quality of life and satisfaction with life of patients before, 1 year and 3 years after performing the surgery of an isolated apical defect using BSC synthetic mesh.

Addison's disease (AD) is a rare condition, but its prevalence in Europe has been steadily rising. Its initial presentation might be a life-threatening event termed adrenal crisis (AC), which is particularly likely to happen during situations of increased biological stress, such as septic illness, general anesthesia, surgery, or trauma. AD can appear as an isolated clinical entity or together with other autoimmune conditions, such as autoimmune thyroiditis, pernicious anemia, or autoimmune primary ovarian insufficiency (POI). In this review, we underline the relationship between AD and POI with a special regard for patients with POI who might develop AD. Due to the nonspecific symptoms of AD, patients often consult multiple specialists before receiving a proper diagnosis, which delays the recognition of AD Ordering basic screening tests might facilitate an early detection of AD and prevent possibly fatal complications of the disease.

Engaging in sexual activity prematurely can lead to adverse emotional consequences for women. Current observational study suggests that such behavior may increase self-esteem sensitivity and trigger heightened feelings of remorse among adolescent girls. Additionally, insufficient contraceptive measures after sexual activity could potentially result in pregnancy and childbirth. Nevertheless, there is a noticeable lack of focused research on the significant reproductive issue of a potential connection between early sexual activity and postpartum depression in females. To address this gap, we have conducted a Mendelian randomization analysis, using the initiation of sexual activity as the exposure variable and postpartum depression as the outcome variable.

Septic abortion is one the leading causes of maternal morbidity and mortality, due to severe complications including pelvic inflammatory disease and sepsis. Preterm premature rupture of the membranes may initiate intrauterine infection which may spread further, to cause an intra-peritoneal abscess which, without adequate treatment, leads to life-threatening consequences of septic shock. The case report presents a 27-years-old woman, in 19th week of first gestation, who presented to the emergency department due to fever and lower abdominal pain. Upon admission to gynecology department gynecological examination, transvaginal ultrasound, cervical and urine bacterial cultures and blood tests were conducted, and empirical intravenous antibiotics were administered immediately. Cervical swab revealed Ureaplasma urealyticum infection, no urine infection was detected, C-reactive protein and procalcitonin were highly elevated. Upon elevation inflammatory markers, non-reactive of the antibiotic's treatment, a further gynecological examination revealed preterm premature rupture of the membranes and due to high risk of sepsis, abortion was pharmacologically induced following patients' informed consent. As transvaginal ultrasonography revealed incomplete abortion, dilation and curettage was performed. The antibiotics treatment was continued, yet due to further increase of abdominal pain and elevation of inflammatory markers, computer tomography revealed an intra-peritoneal abscess, measuring 68 x 90 x 90 millimeters. Multidisciplinary cooperation with surgery and interventional radiology lead to percutaneous drainage of the abscess and patient's full recovery. Preterm premature rupture of the membranes and septic abortion is a rare cause of intra-peritoneal abscesses, yet, upon persevering symptoms, and no evident transvaginal ultrasound findings, computer tomography may prove effective in the diagnostic process.

To assess the diagnostic efficacy of integrated chromosomal microarray analysis (CMA) and whole-exome sequencing (WES) in prenatal CHD diagnosis among diabetic pregnancies and examine potential gene-environment interactions affecting cardiac morphogenesis.

The French Ambulatory Cesarean Section (FAUCS) is an extraperitoneal cesarean technique aimed at enhancing maternal recovery and reducing postoperative morbidity. While early trials suggest certain benefits over conventional cesarean section (CS), real-world data remains scarce. This study compares maternal and neonatal outcomes between FAUCS and CS in a prospective cohort, with emphasis on perioperative recovery.

This article aimed to systematically review the literature on smooth muscle tumors of uncertain malignant potential, known as STUMPs. These tumors pose both diagnostic and therapeutic challenges.

Obesity negatively affects female fertility and pregnancy outcomes. Bariatric surgery improves weight, metabolism, and fertility, but concerns remain about maternal and neonatal outcomes. To evaluate reproductive and perinatal outcomes in Polish women who conceived after bariatric surgery (MOMBARIS 2).

We aimed to evaluate the effect of continuous epidural block combined with free positioning on the genital tract injury in parturients undergoing vaginal delivery.

To identify novel marker genes to predict potential gestational diabetes mellitus (GDM) patients.