Antenatal administration of a single course of corticosteroids before 34 weeks of gestation is associated in the neonatal period with a significant reduction of respiratory distress syndrome (RDS), intraventricular hemorrhage (IVH), necrotizing enterocolitis (NEC) and death, and possibly in childhood with a reduction of cerebral palsy and increased psychomotor development index and intact survival. However, this treatment could be associated with insulin resistance in adulthood and with an increase in mental and behavioural disorders as well as more infections in childhood when birth finally occurs at term. Because of a favourable benefit/risk ratio, antenatal administration of a single course of corticosteroids is recommended for women at risk of preterm delivery before 34 weeks. Repeated antenatal corticosteroid administration is associated in the neonatal period with respiratory benefits but dose-dependent decreased birth weight and, in childhood, with possible neurological impairment. Therefore, this strategy is not recommended. There are two possible strategies for improving the benefit/risk ratio of treatment: reducing the dose or improving the timing of administration. Although it was not possible in a French trial to demonstrate the non-inferiority of a 50% dose reduction on the occurrence of severe RDS, survival without severe neonatal morbidity after half-dose was identical to that after full-dose. The results of further trials and follow-up of these children are therefore required before any conclusions can be drawn about dose reduction. Strategies to improve the timing of treatment have never been evaluated. In conclusion, antenatal corticosteroid administration is recommended to every woman at risk of preterm delivery before 34 weeks of gestation. Strategies aimed at improving the benefit/risk ratio of this treatment are still being evaluated.

Unintended pregnancies are more strongly associated with the risk of intimate partner violence (and/or sexual violence). While healthcare professionals are on the front line of screening, and guidelines recommend systematically asking about violence, such cases are rarely detected. This article aims to measure the impact of the WAST questionnaire in screening for intimate partner violence during pre-abortion consultations and its acceptability among healthcare professionals.

Congenital anomalies of the kidney and urinary tract (CAKUT) account for one-third of all congenital malformations detected by ultrasound. With the introduction of chromosomal microarrays, over 50 genes involved in CAKUT have been identified. The main objective of our study was to assess the contribution of chromosomal analysis performed for CAKUT within our fetal diagnosis and treatment center.

In obstetrics, walking or ambulatory epidural analgesia (APDD) represents an evolution of non-ambulatory epidural analgesia (APD), allowing women to maintain mobility during labor. In a context of increasing demand for more physiological childbirth, it is important to assess its impact on maternal satisfaction and obstetric safety. This article aims to compare maternal satisfaction and obstetric outcomes between women who received APDD and those who received non-ambulatory APD.

Exceeding the legal working hours of residents, particularly in on-call specialties such as obstetrics and gynecology, raises significant issues regarding patient safety, work-life balance, and training. Despite European regulations limiting weekly working hours to 48, available data indicate a systematic overrun, particularly on weekends, without adequate compensatory time off.This study aimed to compare the weekly working hours of residents between a period before the implementation of compensatory days off and a subsequent period. Secondary objectives included assessing the feasibility, impact on annual leave, theoretical training days, and clinical activity related to the compensatory rest.

Ectopic Pregnancy is defined as the presence of a pregnancy or pregnancy residue outside the uterine cavity, with a prevalence of approximately 2%. Tubal ectopic pregnancy is defined as the presence of a pregnancy or pregnancy residue in the extra-myometrial portion of the fallopian tube (isthmus, ampulla, or fimbriae), and accounts for 96 to 99% of ectopic pregnancy locations. Management of tubal ectopic pregnancy should depend on both its activity and whether it is symptomatic or not. Regarding emergency management of tubal ectopic pregnancy, it is recommended not to consider expectant management for patients with symptomatic tubal ectopic pregnancy, nor for patients with active tubal ectopic pregnancy (Strong recommendation, low quality of evidence). It is recommended to offer expectant management as an alternative to medical treatment with MTX (methotrexate) for patients with non-active and asymptomatic tubal ectopic pregnancy (Strong recommendation, low quality of evidence). It is recommended to offer expectant management as an alternative to surgical treatment for patients with non-active and asymptomatic tubal ectopic pregnancy (Strong recommendation, very low quality of evidence). In cases of expectant management of tubal ectopic pregnancy, it is strongly recommended to systematically re-evaluate the patient clinically and biologically at 48hours (Strong recommendation, low quality of evidence). If hCG levels decrease by more than 15% at 48hours, it is recommended to continue monitoring weekly until negativity, provided there are no signs of symptomatic tubal ectopic pregnancy (Strong recommendation, very low quality of evidence). If an expectant approach is chosen, and there is an increase in hCG levels of more than 15% at 48hours or the tubal ectopic pregnancy becomes symptomatic, it is recommended to discontinue expectant management (Strong recommendation, low quality of evidence). Regarding medical treatment of tubal ectopic pregnancy, it is recommended not to favor a multi-dose protocol over a single-dose protocol to increase the success rate of MTX treatment (Strong recommendation, moderate quality of evidence). It is recommended to prefer the single-dose MTX protocol over the multi-dose protocol to limit the risk of adverse effects (Strong recommendation, high quality of evidence). It is also recommended not to systematically combine mifepristone treatment with an MTX injection to improve the efficacy of medical treatment for tubal ectopic pregnancy (Strong recommendation, high quality of evidence). Regarding surgical management, in a patient with tubal ectopic pregnancy, it is recommended to perform either salpingotomy or salpingectomy with regard to fertility (Strong recommendation, high quality of evidence). It is recommended not to perform tubal expression in order to reduce morbidity compared to salpingotomy (Strong recommendation, very low quality of evidence).

Endometriosis is a chronic disease affecting approximately one in ten women of reproductive age. In cases of chronic pain associated with impaired quality of life, a multidisciplinary and integrative approach is recommended. In this context, a therapeutic patient education (TPE) program specifically dedicated to endometriosis was implemented in 2016. This article aims to describe the development and evolution of this program, as well as its evaluation by patients and participating healthcare professionals.

quantify and describe the reasons for complaints in maternity, then identify patients at risk of complaining.

Assessing management practices for pelvic inflammatory disease (PID) complicated by tubo-ovarian abscesses (TOA) at Besançon University Hospital since the 2018 French guidelines.

Hysteroscopic resection of submucosal fibroids is an effective technique to reduce menometrorrhagia and improve fertility. Identifying predictors of two-step resections is essential to optimize preoperative counseling and surgical planning. The objective of this retrospective study was to assess predictive factors previously reported in the literature.

The changes associated with menopause and perimenopause significantly impact women's physical, emotional, mental, and social well-being, affecting their daily activities and overall quality of life, regardless of the severity of their symptoms. Therefore, it is crucial to explore the role of high-quality health education, not only for women themselves but also for healthcare professionals, in order to provide better support during this critical life stage. This study aims to examine educational strategies that could enhance the management of symptoms in women experiencing menopause or perimenopause. A systematic review was conducted following the PRISMA guidelines, utilizing the PICO model for article selection. The search covered multiple databases (Medline, EBSCO, Web of Science, Cochrane Library, PsycINFO, PEDro) from December 2024 to March 2025, focusing on studies that assessed the impact of educational interventions on the health of women in this demographic. Out of 584 articles identified, 10 were selected after a rigorous screening process. Primarily consisting of randomized controlled trials, these studies show that educational programs effectively increase knowledge about menopause, alleviate symptom severity, and improve women's quality of life. Group-based approaches and individualized interventions were found to be particularly effective, especially when they integrated lifestyle factors such as diet, physical activity, and mental health. This study underscores the significant benefits of health education programs in supporting women through menopause and perimenopause. However, there remain gaps, particularly in raising awareness of these issues. Strengthening training for healthcare professionals and engaging more partners involved could significantly enhance women's well-being during this important life transition.

Myelomeningocele (MMC), also known as Spina Bifida, is a congenital malformation of the spinal cord that results in a complex disability including motor deficits, sphincter disorders and cerebral anomalies. Benefit of fetal MMC surgery has been demonstrated since 2011, but remains partial, with persistent motor and sphincter disorders. We have developed an adjuvant treatment to improve spinal cord repair during fetal surgery: a patch composed of umbilical cord-derived mesenchymal stromal cells (UC-MSCs). Our in vitro and in vivo experiments in the ovine model of MMC demonstrated that the UC-MSC patch improves motor and urinary functions by promoting neuronal preservation in the spinal cord. We also confirmed the absence of maternal, fetal, and neonatal adverse effects. Our hypothesis is that this adjuvant therapy can similarly improve spinal cord repair in human fetuses, thereby improving clinical outcomes in affected children. The goal of the PRIUM-Cell clinical trial is to assess the use of UC-MSC patches as an adjuvant therapy during open fetal surgery for MMC in humans.

To present current therapeutic management of breast cancer in the era of de-escalation in breast cancer treatment centres in Abidjan.

The main objective is to create a training program dedicated to the management of obstetric anal sphincter injuries (OASIS). The secondary objective is to evaluate the educational benefits.