Brucella canis infections are poorly understood in humans and difficult to diagnose, with low blood culture yields. Serological diagnosis was introduced in Chile in 2017.

Mpox (formerly known as monkeypox) is an emerging zoonosis caused by the Mpox virus (MPXV), which has raised global concern.

The perception of academic mistreatment among medical students is associated with burnout, emotional disorders, and poorer professional performance. Conversely, a positive environment that promotes respectful teaching can enhance empathy, reduce burnout, and increase student satisfaction. This study examines perceptions of respectful teaching and its associations with demographic and academic characteristics among medical students in Chile.

In a small percentage, multiple myeloma (MM) lacks a measurable monoclonal component, which is termed non-secretory (NS) MM, which includes oligosecretory, true NS and non-producing NS MM (NP). The latter is notable for complete and true absence of paraprotein production. We report a case of a 66-year-old male, studied for low back pain and vertebral lytic lesions, whose blood analysis showed only hypogammaglobulinemia, with no monoclonal component. However, the vertebral biopsy identified a plasma cell tumor. Bone marrow study showed pathological plasma cells without Kappa or Lambda production. With a diagnosis of MM NS NP, he received therapy, achieving complete remission. Extremely infrequently, this group presents a higher incidence of bone lesions and t(11;14) translocation. Therapy follows the general guidelines in MM. The difference lies in the follow-up, which considers myelogram and PET-CT, in addition to monitoring of organic damage.

Tonsillar actinomycosis is a rare chronic disease that affects tonsillar tissue secondary to infection by anaerobic bacteria in the oral cavity. It usually presents as tonsillar hyperplasia and may mimic malignancy. We present the case of a patient referred from the pediatric department with severe unilateral tonsillar asymmetry with suspicion of malignancy. An imaging study showed tonsillar hyperplasia with no signs of local dissemination. The definitive diagnosis was made by excisional biopsy and histopathological study. An infectious disease evaluation indicated complementary treatment with high-dose penicillin-derived antibiotics, which achieved complete resolution of the clinical picture and no recurrent infections.

To evaluate and correct the reported sensitivity and specificity values of DART (Diagnóstico Automatizado de Retinografías Telemáticas), an automated Artificial Intelligence based (AI-based) screening tool used for diabetic retinopathy (DR) detection in the Chilean public healthcare system, by employing the appropriate gold standard and conditional probability.

This study evaluates regional disparities in access to treatment and preventive screenings for high-mortality non-communicable diseases (NCDs) -specifically cancer and diabetes- in Chile, using data from the 2022-2023 National Health, Sexuality, and Gender Survey (ENSSEX).

The implementation of the hospitalist model (HM) in public hospitals across Latin America has been scarcely documented. In Chile, the Diagnosis-Related Groups (DRG) system enables standardized analysis of hospital performance; however, its longitudinal behavior in the context of organizational reform remains underexplored.

Graphic medicine is defined as the intersection between comics, Ilustration and the field of medicine. The concept was introduced by British physician Ian Williams in 2007 and has since evolved, offering a wide range of applications that have influenced both healthcare delivery and the education of health professionals. Today, this form of visual literature is experiencing a global rise, closely tied to the development of the medical humanities since the late 1990s. In particular, narrative medicine -the most recent branch of the medical humanities- has embraced graphic medicine as a powerful tool to better understand the human condition and patient subjectivity.

Recently, there has been a surge in technological tools designed to automate tasks across various areas of health sciences, including the identification of evidence used in the development of evidence syntheses that inform clinical practice guideline (CPG) recommendations. Simultaneously, there has been a significant increase in the production of systematic reviews, meaning that much of the relevant evidence is already included in existing reviews.

Pancreatogenic diabetes is a specific form of diabetes secondary to exocrine pancreatic disease. It is often misclassified or confused with other types of diabetes. It is not a single clinical entity but occurs in association with various exocrine pancreatic disorders, through diffe-rent mechanisms of hyperglycemia. This condition is associated with an increased risk of hypoglycemia, making close clinical monitoring essential.

The use of alternative medicine treatments, such as Schisandra chinensis, has a long-standing history. While numerous active compounds are available on the market, with various benefits attributed to their use, reports of adverse events remain limited. However, significant interactions have been documented between these compounds and the CYP3A enzymatic system, which plays a key role in the metabolism of xenobiotics and endogenous substances. Inactivation of this system has the potential to disrupt coagulation processes, posing serious health risks. Clinical Case: We report the case of a patient who developed spontaneous subdural and subarachnoid hemorrhage and de novo immune thrombocytopenia following the initiation of a multi-component tablet containing Schisandra chinensis. Conclusions: The indiscriminate use of alternative medicine therapies may result in severe, acute, and disabling adverse effects, even in the absence of prior reports of such reactions. Increased awareness and further research are essential to better understand the potential risks associated with these treatments.

Intestinal obstruction (IO) during pregnancy is a rare and serious complication, with sigmoid volvulus (SV) being the most common cause. We present the case of a 28-year-old primigravida at 33+4 weeks of gestation who presented with abdominal pain, nausea, and four days of no bowel movements. IO was diagnosed via computed tomography. A cesarean section was performed, followed by a sigmoidectomy and rectosigmoid anastomosis for ischemic SV. Both the mother and newborn had favorable outcomes. Diagnosing SV in pregnancy is challenging due to symptom overlap with normal pregnancy. Imaging is crucial for timely diagnosis, though radiation exposure must be carefully considered. Prompt management is essential to reduce maternal and fetal mortality, which can reach 50% in cases complicated by perforation.

Atopic dermatitis (AD) is a common chronic inflammatory disease with a variable course, particularly prevalent in the pediatric population. Targeted therapies-such as monoclonal antibodies (mAbs) and Janus kinase (JAK) inhibitors-represent emerging treatment options. Dupilumab was the first mAb approved by the U.S. Food and Drug Administration (FDA) for the treatment of severe AD.