Oral Corticosteroid Use During Pregnancy and the Risk of Gestational Diabetes
Oral corticosteroids (OCSs) are increasingly used during pregnancy for various conditions due to their immunosuppressive and anti-inflammatory properties. However, OCSs may induce insulin resistance, potentially contributing to gestational diabetes, and limited studies have examined this association.
Antibiotic Prophylaxis in Patients With Cirrhosis Presenting With Variceal Bleeding-Are We Treating the Past?-Reply
Characteristics of Speakers at US FDA Advisory Committee Meetings on Drug Approval
Implementing Benzodiazepine Deprescribing in the Primary Care Clinic
Cardiometabolic Parameter Change by Weight Regain on Tirzepatide Withdrawal in Adults With Obesity: A Post Hoc Analysis of the SURMOUNT-4 Trial
In the SURMOUNT-4 trial, most adults with obesity who had tirzepatide withdrawn following a 36-week treatment regained weight. The association between the degree of weight regain and cardiometabolic parameters after tirzepatide withdrawal is unknown.
Durability of Respiratory Syncytial Virus Vaccine Effectiveness Among US Veterans
A single respiratory syncytial virus (RSV) vaccine dose is recommended for older adults and persons at increased risk for severe RSV. Clinical information on the long-term effectiveness of RSV vaccines is needed.
Frailty Assessment for Decision-Making in Older Patients With Acute Coronary Syndrome-Reply
Physical Accessibility of Medicines in Countries Hosting Trials for FDA Approvals
Populations participating in clinical trials should benefit from resulting interventions, according to ethical guidance. Yet, exploratory studies show low- and middle-income countries (LMICs) participating in trials for US Food and Drug Administration (FDA) approvals lack timely access to the medicines they test, raising exploitation concerns.
The Importance of Real-World Evidence to Inform RSV Vaccine Guidance
Antibiotic Prophylaxis in Patients With Cirrhosis Presenting With Variceal Bleeding-Are We Treating the Past?
Frailty Assessment for Decision-Making in Older Patients With Acute Coronary Syndrome
US Food and Drug Administration Competitive Generic Therapy Approvals and Drug Competition
