To evaluate the non-inferiority of mydriatic eye drops administered through a commercially available spray (Optejet, Hyperion DeFi, Inc.) compared to standard eye drops on pupillary dilation in children.

The American Academy of Ophthalmology Recommendations on Screening for Hydroxychloroquine (HCQ) Retinopathy are now a decade old. This revision provides an update, based on current knowledge. Major points and changes are: NATURE OF TOXICITY: The retina typically remains clinically normal for many years on HCQ, but there is an unpredictable point at which signs of toxicity may develop.

To evaluate the efficacy and safety of OT202, a first-in-class, dual-target kinase inhibitor of spleen tyrosine kinase (Syk) and vascular endothelial growth factor receptor 2 (VEGFR-2), for treating moderate-to-severe dry eye disease (DED).

To follow up the previously published comparison of aflibercept 8 mg at extended dosing intervals versus aflibercept 2 mg every 8 weeks (2q8) in patients with diabetic macular edema (DME) through 48 weeks, we now report efficacy, durability, and safety analyses through 96 weeks.

To explore the progression predictors of myopic maculopathy in highly myopic patients following posterior scleral contraction (PSC).

We aimed to identify occurrence rates and associated risk factors of major complications following strabismus surgery in a very large cohort.

To characterize the detailed natural history of ellipsoid zone (EZ) loss progression in Macular Telangiectasia Type 2 (MacTel) and to identify structural predictors of disease acceleration using demographic and OCT-based parameters.

Although traditionally associated with herpes zoster ophthalmicus (HZO), the predictive significance of Hutchinson's sign (HS, or nasociliary nerve involvement) for ocular complications has recently been debated. We conducted a systematic review and meta-analysis to evaluate the association between HS and ocular involvement in HZO.

In this retrospective cohort study of 5,690 adults ≥ 65 years with non-traumatic corneal perforations, Black and older patients were less likely to receive keratoplasty, while older and lower-income patients more often underwent enucleation/evisceration.

To evaluate the proportion of subjects with, and anatomical predictors of, persistent angle-closure five years after laser peripheral iridotomy (LPI) in primary angle-closure suspects (PACS), and to assess anterior segment anatomical changes over the 5-year follow-up.