To map the evidence on nurses' roles and contributions in deprescribing within the multidisciplinary team across all clinical settings.

Non-suicidal self-injury is highly prevalent among adolescents with mood disorders. It not only severely jeopardizes their physical and mental health but also imposes a substantial burden on families. Nurses working in psychiatric settings frequently report challenges in providing care to these young people, often experiencing negative emotional impacts and occupational burnout. The personal experiences of non-suicidal self-injury, and how they intersect with the broader socio-cultural context to influence behavior in this population, are not well understood, thereby hindering the development of effective nursing interventions.

Social participation significantly promotes health in older adults with chronic multimorbidity. However, their needs and characteristics of social participation demonstrate substantial heterogeneity due to multidimensional influences. Current standardized community service models inadequately address this population's diverse needs. User personas, as a group classification model derived from integrating the characteristics of target populations along specific dimensions, can provide a basis for addressing the current challenge in which standardized community services fail to meet the diverse needs of this population.

New digital health services are continuously developed, implemented, tested, and refined to meet diverse health and system needs. With the rise in non-communicable diseases, these services are increasingly integrated into care processes. However, the effectiveness of digital health services varies across time and settings, highlighting the need to evaluate their effectiveness longitudinally and in specific settings.

Paediatric burn injuries pose a critical global health challenge, affecting millions of children annually. Beyond the immediate physical harm, burns disrupt developmental trajectories, leaving enduring psychological, physical, and relational impacts as children transition into adulthood. While advancements in acute care have improved survival rates, understanding the dyadic recovery process between parent and children remains underexplored. The prolonged and complex nature of post-burn recovery necessitates sustained caregiver support, emphasising the need to examine how parent-child dyads experience and collectively navigate this journey.

Older adults living with physical disabilities in residential care homes are at elevated risk for depression and loneliness, which negatively impacts their quality of life. Immersive virtual reality is an evolving modality that engages older adults in therapeutically oriented activities to address these mental health challenges.

Occupational fatigue among healthcare professionals is a complex, multifaceted issue associated with increased likelihood of medical error, compromised patient safety and negative impacts on staff mental and physical health. While safety-critical sectors such as aviation and rail have implemented formal systems to manage fatigue-related risks, it remains unclear whether similarly structured approaches exist or operate effectively within healthcare.

Chronic underfunding of the long-term care sector, coupled with increased complexity of care, has deteriorated working conditions and contributed to severe staffing shortages of healthcare workers globally. While previous reviews have examined the association between long-term care staffing and care outcomes for residents, none have examined specifically how staffing structures affect the care-workers themselves.

Problem drinking and illicit drug use among healthcare workers (i.e., physicians and nurses) may impair their attention and cognitive functioning, thereby increasing the risk of medical errors and diminishing the quality of patient care.

Childhood functional constipation, a common concern within child healthcare, necessitates oral and rectal medical treatments, that are mostly administered by parents in the home environment. It is important to gather children's perspectives in child- and family-centred care. The private nature of toileting, bowel movements, and faecal incontinence are areas of taboo and stigmatisation. Research is scarce on how children perceive this common but private situation of oral and rectal constipation treatment.

Randomised controlled trials demonstrated the effectiveness of midwife continuity of care. Further assessment can be achieved by extending causal inference to non-randomised data and study designs for comparative research.

The need for skilled in-home nursing care is growing, but the home health nursing workforce faces challenges with job turnover, fueling the concern that the supply of these nurses will be inadequate to meet demand.

Informal caregivers are integral to the long-term care of people with Parkinson's disease but often face substantial caregiving burden, which negatively affects both caregivers and care recipients. Despite its significance, there is no existing systematic review or meta-analysis that examines the significance of all potential factors using an appropriate conceptual framework.

Cancer-related cognitive impairment is prevalent in adult cancer survivors, negatively impacting their quality of life. Cognitive rehabilitation has emerged as a potential intervention to improve cancer related cognitive impairment. While several systematic reviews have been published primarily focusing on qualitative analysis, a comprehensive pairwise and network meta-analysis of randomized controlled trials is conducted to quantitatively synthesize and compare the effectiveness of various cognitive rehabilitation in improving cancer related cognitive impairment.

Caring for unstable patients in a general ward is a challenging task for nurses and impacts patients' safety. To assist nurses in detecting and managing patient deterioration, the nurse-led Rapid Response Team has been implemented worldwide for over 25 years with divergent results regarding reduced patient mortality, cardiac arrest rates, and admissions for intensive care. To develop new initiatives targeting well-documented challenges embedded in using the nurse-led Rapid Response Team, research-based knowledge from a broader perspective on the Rapid Response Team is crucial. This study evaluated how and for whom the nurse-led Rapid Response Team works.

Global crises, such as pandemics and armed conflicts, highlight the need for resilient healthcare systems. Nurse middle managers play a critical meso-level role in bridging frontline staff and senior leadership, yet their crisis experiences remain underexplored.

Sickle cell disease is one of the most common inherited monogenetic blood disorders. People living with sickle cell disease experience both acute pain and long-lasting complications, leading to co-morbidities which impact their quality of life. Palliative care is both under-reported and under-utilised for people living with sickle cell disease despite the profound impacts of this illness across their lives.

Older people residing in aged care homes often have complex health needs that can lead to hospitalisations, some of which are potentially avoidable. To address this, nurse-led or nurse-involved interventions have been implemented to reduce unnecessary hospital presentations.

With the proposed "aging in place" and "dementia-friendly community" policies, communities have become key places in which to support people with dementia. As core members of a community, residents could play a significant role in making full use of community resources to help people with dementia.

Embedded, interventional health systems research is increasingly promoted to better understand and strengthen the performance of health systems. However, for these forms of research, boundaries between clinical care, quality improvement, and public health can be blurred, and ethical implications and frameworks to draw upon are unclear. While there is evolving ethical guidance, few health systems studies have documented ethical dilemmas experienced post ethics approval, and the value of support processes introduced to manage arising dilemmas. In this discussion paper, we share our approach to handling the ethical dilemmas that arose while conducting embedded interventional health systems research in public-sector newborn units in Kenya.