JACC-Clinical Electrophysiology

Slow Conducting Anatomical Isthmus and VT Inducibility in Repaired Tetralogy of Fallot: It Takes More Than 2 to Tango
Shah M and Blom NA
Comparison of Monopolar and Bipolar Pulsed Field vs Radiofrequency Ablation on Coronary Artery Injury in a Swine Model
Gerstenfeld EP, Bifulco S, Lehn L, Soltis B, Curtis M, Baldo C, Shuros A, Speltz M and Garrott K
Pulsed field ablation (PFA) has the advantage of tissue selectivity but is known to cause coronary artery (CA) spasm and injury. The effect of changes in PFA waveform on CA injury has not been adequately explored.
Early and Late Myocardial Effects of Proton Beam Cardiac Radioablation: Insights From Gene Expression Analysis
Hirao T, Suda M, Rettmann ME, Deisher AJ, Wight JA, Koya T, Newman LK, Tchkonia T, Kruse JJ, Shumway DA, Merrell KW, Asirvatham SJ, Kirkland JL, Packer DL and Siontis KC
Cardiac radioablation (CRA) is an emerging treatment modality for refractory ventricular tachycardia. The mechanisms underlying the antiarrhythmic effect of CRA remain incompletely understood.
Principal Component-Referenced Multipolar Mapping to Localize an Arrhythmic Source From Various Depths of the Myocardium
Denham N, Massé S, Abderrahman Y, Asta J, Lai P, Rodriguez H, Tsoref L, Nemaire M, Anderson R, Vigmond E and Nanthakumar K
Intramural premature ventricular contraction (PVC) mapping is limited by the ability of unipolar and bipolar electrograms (EGMs) to discriminate near from far-field activity.
A Phenotype-Enhanced Variant Classification Framework to Decrease the Burden of Variants of Uncertain Significance in Type 2 Long QT Syndrome
Neves R, Crotti L, Bains S, Bos JM, Ye D, Dagradi F, Musu G, Spiezia F, Pedrazzini M, Giovenzana FLF, Cerea P, Giudicessi JR, Schwartz PJ and Ackerman MJ
Pathogenic/likely pathogenic variants in the KCNH2-encoded Kv11.1 potassium channel cause type 2 long QT syndrome (LQT2). Despite the updated 2015 American College of Medical Genetics (ACMG) variant interpretation guidelines, the burden of KCNH2 variants of uncertain significance (VUS) in patients evaluated for long QT syndrome (LQTS) remains ∼30%. Previously, we developed and validated phenotype-enhanced (PE) ACMG variant adjudication for type 1 long QT syndrome.
Social Determinants of Health in Atrial Fibrillation Care: Are We Asking the Hard Questions?
Cheung CC and Kalman JM
Ventricular Pre-Excitation, Long QT Syndrome, and Polymorphic Ventricular Tachycardia
Belhassen B
REPLY: Ventricular Pre-Excitation, Long QT Syndrome, and Polymorphic Ventricular Tachycardia
Bazan V and Villuendas R
Impact of Steroids on Managing Iatrogenic Pericardial Diseases After Electrophysiology Procedures
Yeo YH, Wong HKK, Vignarajah A, Vigneswaramoorthy N, Sankar P, Goldstein J and Mehta NK
Focal-Bipolar Pulsed Field Ablation of Inaccessible Epicardial Left Ventricular Summit Arrhythmia
Futyma P and Zarębski Ł
Elevating Practice: The Unique Value of the American College of Cardiology for Cardiac Electrophysiologists
Mason PK, Akoum N, Haloot J, Kabra R, Nedios S, Needleman M, Tamirisa KP and Cheung JW
Biatrial Flutter in Repaired Tetralogy of Fallot: Complementary Role of Activation and Entrainment Mapping in Understanding the Mechanism of a Complex Atrial Arrhythmia
Ahmed I, Denham NC and Nair K
Multimodal Strategies to Reduce Health System-Wide Opioid Utilization After Cardiac Implantable Electronic Device Procedures
Zghaib T, Walsh M, Crisfulla K, Ramos C, Lucas K, Clay-Weinfeld K, Austin MP, Lin D, Frankel DS and Markman TM
Catheter Ablation Outcomes and Life Expectancy in Very Elderly Atrial Fibrillation Patients: The REHEALTH AF Study
Hirata S, Okumura Y, Nagashima K, Watanabe R, Yokoyama K, Matsumoto N, Kato T, Fukaya H, Hayashi H, Nakahara S, Shimizu W, Iwasaki YK, Fujimoto Y, Mukai Y, Ejima K, Otsuka T, Suzuki S, Murakami M, Kimura M, Harada M, Koyama J, Yamane T, Tokuda M, Takami M, Shoda M, Harada T, Nakajima I, Hiroshima K, Tanimoto K, Kumagai K, Okada A, Kobayashi H, Watari Y, Hatsuno M, Hayashi T, Tachibana E, Iso K, Sonoda K, Aizawa Y, Fukuoka R, Chikata A, Inoue M, Sakagami S, Minamiguchi H, Makino N, Ichikawa M, Haruta H, Hiro T, Okubo K, Arai M, Arima K, Kihara H, Miyanaga S, Fukuda Y, Oiwa K, Koyama Y, Kurihara T, Akabane M, Ishikawa N, Kusano K, Miyamoto K, Tabuchi H, Shiozawa T, Miyamoto K, Mase H and Murotani K
Evidence regarding the benefits of catheter ablation in patients aged ≥80 years with nonvalvular atrial fibrillation (AF) remains limited.
2:1 Atrioventricular Block With Exercise-Induced Wide QRS Tachycardia 10 Years After Slow Pathway Ablation
Dadon Z, Medina A, Michowitz Y and Belhassen B
Conduction System Pacing for Cardiac Sarcoidosis: A Mission Impossible for LBBAP?
Bressi E and Kron J
REPLY: New-Onset RBBB After TAVRA Potential Danger Signal
Michowitz Y and Belhassen B
Detection of Titin-Associated Electrocardiography Features in Dilated Cardiomyopathy Using Conventional and Deep Neural Network Analysis
Heymans ABM, van de Leur RR, Wang P, González-López E, Venner MFGHM, Beelen NJ, Muller SA, Mora-Ayestarán N, Ramos N, Faassen IME, Stroeks SLVM, Soria M, van der Crabben SN, Ter Bekke RMA, van Es R, Vernooy K, Te Riele ASJM, García-Pavía P, Heymans SRB and Verdonschot JAJ
Titin truncating variants (TTNtvs) are the leading genetic cause of dilated cardiomyopathy (DCM). Although recommended, routine genetic testing is frequently not performed owing to resource constraints.
New-Onset RBBB After TAVR: A Potential Danger Signal
Liu JP, Zhang WD, Li H, Yang CG and Zhang HP
Implantable Cardioverter-Defibrillator Use in Patients With Left Ventricular Assist Devices: A Systematic Review and Meta-Analysis
Cherbi M, Gautier P, Benali K, Martins R, Maury P and Delmas C
Predicting Sudden Cardiac Death in Patients With Sarcoidosis Using a Multimodal Artificial Intelligence Model
Lai C, Yin M, Kholmovski EG, Sani MM, Gilotra NA, Chrispin J and Trayanova NA
Patients with cardiac sarcoidosis (CS) are at high risk of sudden cardiac death (SCD), but existing guidelines relying primarily on left ventricular ejection fraction (LVEF) in recommending implantable cardioverter-defibrillator therapy have limited accuracy.