AGING CLINICAL AND EXPERIMENTAL RESEARCH

Vibration-induced illusion of movement is hindered by acute stroke but mostly by aging: a cross-sectional study
Léger B, Auzou P, Fourdrinoy É, Sarrazin M, Celot S, Gay C, de Dieuleveult B, Cohen C, Perrey S and Özsancak C
The proprioceptive and visual systems play a major role in daily tasks by providing continuous feedback to the central nervous system (CNS) for coordinating movements. However, it remains unclear to what extent alterations in the proprioceptive system and CNS affect vibration-induced illusion of movement (VIM) with age and after a stroke. To address this, 29 young (26 ± 7 years), 30 older (63 ± 8 years), and 26 stroke participants (68 ± 12 years) with left arm impairment, all right-handed, received triceps brachii tendon vibration with or without visual feedback of the vibrated arm (with/without vision), as it can modulate the illusion of movement. Vibrations were applied bilaterally in healthy participants and on the impaired left arm in stroke individuals. The illusion was quantified using the Standardized Kinesthetic Illusion Procedure (SKIP) ordinal scale, which evaluates the clearness and the direction of the movement, resulting in a total score on four. While young and older adults achieved higher scores without vision, acute stroke participants did not (Young: µ = 2.62/0.86, p < 0.001, Young: µ = 2.35/0.69, p < 0.001; Older: µ = 1.52/0.63, p < 0.001, Older: µ = 1.03/0.50, p < 0.01; Stroke: µ = 0.85/0.62, p = 0.23). Moreover, young participants reported a stronger illusion than both older and acute stroke participants, and older participants reported a stronger illusion than acute stroke participants. Altogether, these findings suggest that aging alters VIM response, with acute stroke exacerbating this impairment. Finally, in acute stroke participants, a significant negative correlation between age and SKIP total score without vision was observed, highlighting the considerable impact of aging even within a pathological condition.Clinical Trial registration: NCT06218563-2024-01-12.
Health literacy as a buffer: mitigating the impact of Multimorbidity on functional health in older adults
Schönenberg A and Prell T
Multimorbidity is a leading cause of functional health impairments in older adults, affecting Activities of Daily Living (ADL). Health-literacy enables individuals to access, process, and apply health-related information effectively, serving as a strategy to mitigate these effects.
Letter to the Editor: "Global, regional, and national burden of malignant neoplasm of bone and articular cartilage in adults aged 65 years and older, 1990-2021: a systematic analysis based on the global burden of disease study 2021"
Niakan R
The recent publication by Zhang et al. on the burden of malignant neoplasm of bone and articular cartilage in the geriatric population reports age-standardized incidence, prevalence, disability-adjusted life year (DALY), and mortality rates. The authors present age-standardized rates for the 6+ age group based on the Global Burden of Disease (GBD) 2021 study. However, calculating age-standardized measures for a single age group is methodologically inconsistent and may lead to misinterpretation. These measures are designed to compare populations with varying age distributions by applying a uniform age structure. Thus, the GBD 2021 study only offers age-standardized rates for total populations, not specific age groups. Moreover, the 65 + group is not among the predefined age groups in the GBD 2021 study for any health measures. While crude numbers for custom age groups, such as individuals aged 65 years and older, can be derived from the available data, estimating incidence, prevalence, DALY or mortality rates requires complex calculations that cannot be reproduced externally. These limitations raise notable concerns about the reliability of the reported measures and their interpretation.
From age to frailty: redefining chronic pain characterization
Mourelle-Sanmartín P, Lorenzo-López L, Millán-Calenti JC, Andrew MK and Theou O
Correction: Polypharmacy and sarcopenia in hospitalized older patients: results of the GLISTEN study
Agosta L, Bo M, Bianchi L, Abete P, Bellelli G, Cherubini A, Corica F, Di Bari M, Maggio M, Manca GM, Rizzo MR, Rossi A, Landi F, Volpato S and
Predictive validation of a questionnaire for the assessment of social care needs in hospitalized older adults, the geriatric discharge complexity score: a diagnostic accuracy study
Rossi AP, Scattolin A, Melchiori L, Goinavi A, Pasqual A, Rossi K, Commissati S, Bernardi M, Muollo V, Ceolin C, De Rui M and Sergi G
Anticipating discharge challenges in the elderly population is essential to support effective care planning and reduce risks during care transitions. However, there is a lack of targeted assessment tools specifically designed for use in hospital wards to address this need.
The prevalence and associated factors of inappropriate sexual behaviour in psychogeriatric inpatients in a Chinese psychiatric hospital: A cross-sectional study
Da M and Xu L
To investigate the prevalence and associated factors of inappropriate sexual behaviour (ISB) in psychogeriatric inpatients in a Chinese psychiatric hospital.
Association between low handgrip strength and the increased risk of age-related macular degeneration: results from UK biobank cohort study
Wang S, Hong Y, Qu Y, Zheng K, Luo H, Chen R, Jia H, Liu X and Sun X
To determine whether handgrip strength is associated with the incidence of age-related macular degeneration.
The association between body fat distribution and osteosarcopenia in older adults: evidence from the PoCOsteo study
Torabi A, Afrashteh S, Moftian N, Ghalandari H, Farhadi A, Emamat H, Nabipour I and Larijani B
Osteosarcopenia is a syndrome associated with aging, characterized by the simultaneous occurrence of two conditions: osteopenia and sarcopenia. The association between various fat mass distributions across the body and osteosarcopenia is not clear.
The association between age- and sex-related differences in muscle strength and physical performance in Chinese older adults: a 5-year prospective cohort study
Lu X, Xia J, Hu Y, Qian M, Wang L, Yuan Y, Zhao D, Wang S, Zang Q, Liu K, Hu J, Cheng X and Guglielmi G
Evaluating the role of CHG index in predicting stroke risk among adults with varying glucose regulation
Xiao Q, Huang W, Zhuang Y, Chen Y, Peng G and Li Y
Stroke is a significant public health issue, with its risk influenced by various metabolic factors. The Cholesterol, High-Density Lipoprotein, Glucose (CHG) index has been identified as a valid stroke predictor. However, the impact of glucose-metabolic states on the relationship between CHG index and stroke risk remains unclear.
Prevalence of polypharmacy among older adults with diabetes: A systematic review and Meta-Analysis
Satapathy P, Gaidhane AM, Vadia N, Menon SV, Chennakesavulu K, Panigrahi R, Shabil M, Singh M, Sah S, Lingamaiah D, Rao SG, Goh KW, Mawejje E and Bushi G
Polypharmacy, the concurrent use of five or more medications, is prevalent among older adults with Diabetes, a population at elevated risk for medication-related complications. Complex treatment regimens for Diabetes and its comorbidities exacerbate challenges such as medication non-adherence, drug interactions, adverse events, and increased hospitalization risk. This review aimed to estimate the prevalence of polypharmacy among older adults with Diabetes.
The influence of sarcopenia on health-related quality of life among older patients with gastrointestinal cancer: an assessment using the SarQoL questionnaire
Kamińska A, Wąż A, Dziedzic M, Micek A and Konturek A
Sarcopenia, characterized by a progressive loss of skeletal muscle mass and function, significantly affects older adults, particularly those with cancer. Although sarcopenia's negative influence on quality of life (QoL) is acknowledged, data on its specific impact among older hospitalized oncology patients remain limited. The aim of the present study was to assess the health-related quality of life in older patients (≥ 65 years) diagnosed with gastrointestinal cancer using the SarQoL questionnaire and to analyze the association between weight loss and functioning across individual quality of life domains.
Is psychological engagement more important than participation? Volunteer activity and subjective cognitive function in older adults
Shiratsuchi D, Miyake Y, Kuratsu R, Nishi H, Fukumori M, Atae S, Kiyama R, Kosakamoto R, Tanaka H and Makizako H
While previous studies have shown inconsistent associations between volunteer participation and cognitive health in later life, less attention has been paid to qualitative aspects of engagement. This study examined whether psychological engagement in volunteer activities is associated with subjective cognitive function in community-dwelling older adults.
A prospective association between dietary phytate intake and risk of fracture in middle-aged and older adults: a 12-Year prospective cohort study
Bahadoran Z, Mirmiran P and Azizi F
This study aimed to investigate the association between dietary phytate intake and the incidence of bone fractures among adults aged over 50 years.
Relationships between pain, physical activity and sleep quality among older adults with radiographic knee osteoarthritis: findings from the Hertfordshire Cohort Study
Kirkham-Wilson F, Westbury L, Bevilacqua G, Laskou F, Fuggle N and Dennison E
To determine if the relationship between joint pain and sleep quality among individuals with osteoarthritis (OA) differs according to physical activity level among older adults.
Admission lactate and short-term mortality in the geriatric ICU: comparison with established severity scores
Düzgün A and Kalın BS
This study aims to investigate the prognostic value of admission lactate level in predicting 28-day mortality among geriatric patients admitted to the intensive care unit (ICU) and to compare its performance with established severity scores, including APACHE II and SOFA.
Comparative effects of traditional Thai abdominal massage versus prune consumption on constipation and quality of life in elderly women: A randomized controlled trial
Assadollahzadeh A, Ravari A, Assadollahi Z and Mirzaei T
Chronic constipation is common in the elderly, impairing quality of life and increasing healthcare use. While pharmacologic options exist, low-cost non-pharmacological alternatives remain underutilized.
Validity and reliability of assessing strength and balance improvements by videoconference in pre-frail and frail older adults
Perkin OJ, Liang IJ, McKay CD, McGuigan P and Western MJ
Assessing older adults' physical function via videoconferencing technology is acceptable and feasible, enabling researchers and practitioners to monitor mobility remotely. However, validity of remote assessment in pre-frail and frail older adults, and its ability to detect change with intervention, has yet to be established.
Effect of host and gut microbiota-altering interventions on sarcopenia or its defining parameters: a systematic review and meta-analysis of nutrition-based intervention studies
Lapauw L, Amini N, Switsers E, Dupont J, Vercauteren L, Derrien M, Raes J and Gielen E
To investigate effects of host- and gut microbiota (GM)-altering interventions on sarcopenia (parameters).
Associations between muscle quality index and cardiac function in older adults with sarcopenia and obesity
Tan SYT, Wong JJ, Tan GHM, Tan RS, Gao F, Teo LLY, Ewe SH, Lim WS, Tan HC and Koh AS
The increasing co-occurrence of sarcopenia and obesity is associated with morbidity. The muscle quality index (MQI), which measures strength per unit of muscle mass, has been described to detect sarcopenic obesity, but associations with cardiac function are unknown.