Diabetic neuropathy (DN) and nephropathy (DKD) are prevalent microvascular complications in Type 2 diabetes mellitus (T2DM), often evolving silently. Detecting early nephropathy remains a clinical challenge, especially in patients with preserved renal function.

Patient utilization of diabetes technology differs based on sociodemographic and other factors. Underserved patients have reported that providers decline to prescribe continuous glucose monitors (CGMs) and insulin pumps. This qualitative study elucidated provider perspectives regarding facilitators and barriers to the prescription and patient use of diabetes technology.

This study was aimed at evaluating the effectiveness of traditional Chinese exercises (TCEs) in improving both physical and psychological health in individuals with prediabetes.

Diabetes mellitus (DM) and cardiovascular disease (CVD) are interconnected conditions that significantly contribute to global mortality, yet their bidirectional relationship and combined mortality impact remain underexplored.

The aim of this study is to evaluate the real-world prescribing patterns of SGLT2 inhibitors and GLP-1 receptor agonists (GLP-1RA) in patients with newly diagnosed Type 2 diabetes (T2DM), particularly among those with high cardiovascular risks or chronic kidney disease, and to identify demographic, clinical, and system-level factors associated with receiving these medications.

Hyperuricemia remains a critical risk factor for diabetic kidney disease (DKD) currently. Recent studies have confirmed that allopurinol, an inhibitor of xanthine oxidase (XO), does not have any beneficial effects on DKD. However, it is still unclear how uricosurics, such as benzbromarone (BZ), affect the progression of DKD.

[This retracts the article DOI: 10.1155/2014/678123.].

Continuous glucose monitors (CGMs) enhance diabetes management, but disparities exist, particularly among underserved populations in federally qualified health centers (FQHCs). In 2022, a California Medicaid policy change expanded CGM coverage, providing an opportunity to better evaluate barriers to CGM use within primary care in an FQHC.

This study utilized db/db mice and MPC5 cells induced by high glucose as experimental models to examine the protective mechanisms of the traditional Chinese medicine formula TangNaikang (TNK) in mitigating podocyte injury in diabetic nephropathy (DN).

We aimed to explore the relationship of noise exposure in the workplace, genetic risk, and lifestyle with Type 2 diabetes (T2D).

Waist-triglyceride index (WTI) is a novel indicator of insulin resistance that can effectively identify glucose metabolism abnormalities and metabolic syndrome. No study discussed the predictive ability of WTI for incident Type 2 diabetes (T2D) risk from a longitudinal perspective. We aimed to evaluate the relationship between the baseline WTI level and the risk of T2D during follow-up in an elderly cohort.

The insulin-like growth factor (IGF) axis, an evolutionarily conserved system, is critical in regulating cell growth, proliferation, and survival, affecting nearly all organ systems. This axis comprises two growth factors, IGF-I and IGF-II, and six insulin-like growth factor-binding proteins (IGFBPs), modulating IGF activity. Due to their structural similarity to insulin, IGFs can interact with insulin receptors, facilitating glucose uptake in adipose and muscle tissues, suppressing hepatic glucose production, and modulating blood glucose levels. Pregnancy induces unique metabolic challenges, with the IGF axis adapting to support maternal metabolic changes and fetal growth. In pregnancies complicated by prediabetes or diabetes, disruptions in the IGF axis, including altered levels of IGFs and IGFBPs, have been linked to adverse outcomes such as macrosomia and intrauterine growth restriction. This review discusses the role of the IGF system in pregnancies with diabetes, focusing on how dysregulation of IGFs and IGFBPs contributes to pregnancy complications. We emphasize the dual role of the IGF axis in metabolism and growth and evaluate its potential as a therapeutic target in managing high-risk pregnancies.

[This retracts the article DOI: 10.1155/2021/5445349.].

This research explores the impact of glucagon-like peptide-1 receptor agonist (GLP-1RA) on key risk factors associated with kidney and cardiovascular diseases in Indigenous (Aboriginal and/or Torres Strait Islander) and non-Indigenous adults living with Type 2 diabetes, receiving care at a regional health facility in North Queensland, Australia.

Acute ischemic stroke (AIS) patients with diabetes mellitus (DM) have significantly lower brain-derived neurotrophic factor (BDNF) levels compared to nondiabetic patients. However, the impact of BDNF on thrombus characteristics is unclear. The relationship between the plasma BDNF and fibrin ultrastructure of thrombi was investigated.

Disparities in outcomes and technology use in children with Type 1 diabetes (T1D) from underresourced backgrounds are well documented. The feasibility of initiating automated insulin delivery (AID) soon after diagnosis of T1D is less certain in this population. This pilot study assessed the feasibility and acceptability of providing access to the Tandem Control-IQ AID system to children with public insurance soon after T1D diagnosis.

Type 2 diabetes mellitus (T2DM) refers to a chronic metabolic disorder that results from insulin resistance, leading to impaired insulin action and uncontrolled plasma glucose levels. is among medicinal plants that are ethnobotanically used in the management of T2DM. However, there is a paucity of information on its antidiabetic potential. This review is aimed at providing a current understanding of the mechanism of action, potency, and safety of in T2DM therapy.

People with diabetes experience a significantly higher prevalence of mental health issues, particularly depression. This adversely affects their diabetes management and overall health. This scoping review aims to develop a conceptual framework for understanding the connection between depression and diabetes outcomes globally, specifically focusing on intermediary factors that may influence this relationship.

Declined renal function is closely linked to diabetes. However, it remains unclear whether the intraindividual difference between cystatin C- and creatinine-based estimated glomerular filtration rates (eGFRdiff) is associated with diabetes. This study was aimed at examining the association between eGFRdiff and prevalent diabetes in a nationally representative cohort of Chinese adults.

In this study, we investigated whether high-intensity interval training (HIIT) and mixed probiotic consumption, either autonomously or synergistically, could regulate the expression of calcium-binding protein-1 (SMOC-1), insulin resistance (IR), and blood glucose (BG) in male rats with induced diabetes.

Diabetic kidney disease (DKD) is a major global cause of end-stage renal disease. Emerging evidence suggests that hypoxia is a critical factor in the advancement of DKD. Traditional Chinese medicine (TCM) is an effective alternative therapy for DKD. The Qi-Gui-Sheng-Jiang-San (QGSJS) decoction is an effective formula for treating DKD clinically, and its mechanism may be related to regulating hypoxia response, necessitating further investigation and a thorough analysis of the underlying biological mechanisms.