The aim of this study was to evaluate the clinical performance of 2 DNA-based assays (DNA-xGT, DNA-lGT) and 1 RNA-based assay (mRNA), using specimens from women with cervical carcinoma or high-grade cervical lesions (≥CIN3).

The aim of the study was to evaluate the risk for cervical intraepithelial neoplasia II (CIN 2) or worse associated with high-risk (HR) non-16/18 human papillomavirus (HPV) types among women with normal cytology in a screening context.

Cervical acetowhitening is a strong visual cue for lesion identification; however, clinician opinions are subjective and inconsistent. To provide objective evaluation, a machine learning model that enhances colposcopy by automating acetowhite lesion detection in cervical time-series images was developed.

Depth of invasion (DOI) in vulvar squamous cell carcinoma (vSCC) predicts risk of nodal metastasis, with measurement >1 mm dictating the need for lymph node diagnostic procedures. In 2021, the International Federation of Gynecology and Obstetrics (FIGO) changed its advice on how pathologists measure DOI. Some organizations revised guidelines to this "New" method; others continued to endorse the FIGO 2009 "Old" method. This study compares interobserver variation of vSCC DOI using Old and New FIGO measurement strategies.

The aim of the study was to provide recommendations on quality standards for colposcopy and colposcopy training.

The aim of this study was to characterize human papillomavirus (HPV) using a highly sensitive genotyping test on smears collected longitudinally that showed a positive-negative-positive infection pattern with a screening test.

The aim of the study was to evaluate if a teaching session and optional reminders improved frequency of performance of vulvar self-examination (VSE) in a population at increased risk of vulvar cancer.

Dynamic Spectral Imaging colposcopy (DSI), an AI-driven technology, may improve cervical cancer diagnostics. This study aimed to evaluate the cervical intraepithelial neoplasia grade 2 or worse (CIN2+) sensitivity of DSI compared to regular colposcopy in individuals referred due to human papillomavirus (HPV)-positive and/or low-grade cytology.

Practice recommendations for the minimum steps to perform a colposcopy were published in 2017. The goals of this study are to assess if adherence to these guidelines correlates with detection of cervical intraepithelial neoplasia and to analyze factors associated with rates of biopsy during colposcopy.

We set out to evaluate the efficacy and safety of phosphodiesterase-4 inhibitor apremilast for moderate-to-severe genital erosive lichen planus (GELP) in women.

Multicentric, human papillomavirus (HPV) associated lower genital tract disease includes preinvasive and invasive lesions at multiple anatomic sites and can be synchronous or metachronous. Identifying patients with multicentric disease is crucial because of associated high treatment failure and recurrence. This study evaluates clinicopathologic patterns in immunocompetent and immunocompromised patients with multicentric lower anogenital disease.

To assess the use of boric acid and probiotics among patients treated at a tertiary care vulvovaginal health center.

This study aimed to determine the prevalence of anal dysplasia in women who had anal high-risk human papillomavirus (HR-HPV) and/or abnormal cytology in 2012-2014.

The aim of the review evaluates the feasibility and acceptability of human papillomavirus (HPV) self-sampling in underscreened communities to increase cervical cancer screening rates in the United States.

The Pap test is effective for detecting squamous neoplasia, but the interpretation of atypical glandular cell (AGC) remains challenging because of its rarity, complex cytologic features, and interobserver variability. Although AGC represents a small proportion of Pap test diagnoses, it often leads to extensive follow-up. This study aimed to assess whether gynecologic pathology expertise improves diagnostic accuracy and reduces unnecessary interventions in AGC interpretation.

Vulvar health conditions such as lichen sclerosus and vulvodynia are often misdiagnosed or delayed in diagnosis, leading to worsened clinical outcomes. A standardized intake questionnaire for the initial patient visit could improve early detection and management of these complex conditions. This study aimed to develop a consensus-based standardized intake questionnaire for vulvar health clinics using the eDelphi methodology.

Loop electrosurgical excision (LEEP) is the standard of care for high-grade cervical intraepithelial neoplasia. The primary aim of this study was to compare patient-reported outcomes among patients who received local anesthesia (LA) during LEEP with those who received GA.

The study aims are to evaluate the utility of cervical or vaginal human papillomavirus (HPV) status in predicting recurrence of noncervix lower genital tract (LGT) high-grade squamous intraepithelial lesion (HSIL), assess factors associated with HPV positivity, and explore patterns of HSIL surveillance.

The aim of the study was to examine factors associated with timely colposcopy following abnormal cervical cancer screening among patients receiving care at an urban safety-net obstetrics and gynecology clinic.

Timely treatment of anal high-grade intraepithelial lesions (HSIL) prevents progression to anal cancer. Available screening tools (anal Pap test and high-risk human papillomavirus testing) have inconsistent and suboptimal performance, often leading to overreferral to high-resolution anoscopy, the gold standard test for HSIL diagnosis. We aimed to develop and externally validate a clinical prediction model for histologic HSIL to improve triage to high-resolution anoscopy among individuals at increased risk for anal cancer.