The purpose of this study was to compare the perioperative efficacy and safety of neoadjuvant chemoradiotherapy (NCRT) alone versus short-course radiotherapy combined with immunochemotherapy (SCRT + ICT) in patients with proficient mismatch repair (pMMR) rectal cancer.

Chronic anal fissures in patients with Crohn's disease (CD) remain a significant therapeutic challenge, particularly when linked to active perianal disease. Conventional treatments often fail, highlighting the need for alternative approaches. This study explores the efficacy and safety of freshly collected autologous adipose tissue injection (AATI) for treating chronic fissures in patients with CD.

In the Netherlands, approximately 15% of patients with rectal cancer undergo a low Hartmann's procedure (low-HP). This is often preoperatively planned to avoid poor functional outcome or complications, but might be unplanned as a result of intraoperative difficulties. Low-HPs seem to be associated with worse oncological outcomes.

Endoscopic intermuscular dissection (EID) is an emerging technique for resecting early rectal cancer with deep submucosal infiltration. This study reports the short-term outcomes of EID for early rectal cancer from a single-center experience in China.

Transsphincteric anal fistula is a common and challenging diagnosis for patients and surgeons alike. Ligation of the intersphincteric fistula tract (LIFT) following non-cutting seton placement represents an established definitive treatment with many technical variations. Unfortunately, up to 53% of attempted LIFTs fail. We aim to describe a modified LIFT approach and evaluate outcomes at our institution.

The incidence of acute appendicitis in older patients significantly varies from that in younger adults. The coronavirus disease 2019 (COVID-19) pandemic has increased the risk of early post-appendectomy complications (EPAC). This study aimed to investigate the incidence and risk factors associated with EPAC in older patients after appendectomy and to define active COVID-19 infection during surgery as an associated risk factor for EPAC.

Indocyanine green (ICG) lymphangiography for colon cancer has been regarded as a sentinel lymph node (LN) detection tool, but its repeatedly reported suboptimal sensitivity rates suggest that approach aiming to define locoregional lymphatic collector margins might be more efficient in guiding surgeon's decision making. Thus, present study was designed to determine if sensitivity of the latter approach is sufficient to guide resection margins' selection in colon cancer surgery.

Obstructed defecation syndrome (ODS) is a prevalent pelvic floor disorder, often impairing patients' quality of life. Noninvasive therapies, including posterior tibial nerve stimulation (PTNS), have been explored as alternative treatments. This study evaluates the efficacy of bilateral transcutaneous posterior tibial nerve stimulation (BT-PTNS) compared to medical treatment alone in patients with ODS without anatomical abnormalities.

Rectal-sparing strategies for locally advanced rectal cancer are gaining interest owing to favorable oncological results and reduced impact on functional outcomes. In patients managed with watch-and-wait or local excision after neoadjuvant chemoradiotherapy (nCRT), local regrowth occurs in approximately 15-30% of cases. Total mesorectal excision (TME) is the standard treatment for regrowth; however, local excision (LE) may be considered in selected cases to preserve rectal function. This narrative review evaluates clinical and oncological outcomes of patients undergoing LE for suspected regrowth.

In accordance with Enhanced Recovery After Surgery (ERAS) principles, it has recently been suggested that preoperative stoma education protocols be routinely introduced in perioperative care. Potential benefits of such programs include shorter postoperative length of stay (LOS) and decreased readmission following discharge. We designed this systematic review and meta-analysis to further investigate the effect of preoperative stoma education on postoperative outcomes.

Pilonidal sinus disease is a common condition affecting the skin and subcutaneous tissue in the upper natal cleft. Bascom's cleft lift procedure, an established surgical technique, treats the disease by excising the sinus tract, flattening the gluteal cleft, and displacing the incision off the midline (Immerman in Cureus, 2021. 10.7759/cureus.13053; Leventoglu et al. in Colorectal Dis 25:1938-1939, 2023. 10.1111/codi.16701). The seagull excision technique, developed as an alternative to the proven cleft lift procedure, aims to achieve similar surgical goals while offering a different flap design and closure strategy. This video demonstrates the application of the seagull excision technique in a 37-year-old male patient with pilonidal sinus disease.

The National Health System is responsible for 8-10% of total greenhouse gas emissions. Operating rooms are responsible for 60-70% of all hospital waste. Over the last 30 years abdominal surgery transcended from a laparoscopic approach toward a robot-assisted approach. The role of robot-assisted laparoscopic surgery is still debated in some procedures, such as colorectal surgery. The studies available in scientific literature comparing laparoscopic and robot-assisted left hemicolectomy are focused on clinical outcomes. The environmental sustainability of these procedures remains largely unexplored, representing a key area that our study seeks to investigate.

This study aims to compare the intraoperative and postoperative outcomes of single-port laparoscopic Hartmann's reversal (SPLHR) and open Hartmann's reversal (OHR).

Ileocecal resection is the most common surgery in Crohn's disease (CD). As recurrences often occur at the anastomosis it has been questioned whether surgical technique may have a role in its prevention. The Kono-S anastomosis, first described in 2011, has shown potential to reduce anastomotic recurrence while maintaining luminal width and preventing distortion. The classic surgery described was a handsewn anastomosis. Lately a stapled approach has emerged which is less technically demanding, and requires shorter operative time. We compared stapled versus handsewn Kono-S ileocolonic anastomosis in patients with Crohn's disease, evaluating operative time and perioperative outcomes.

This study aimed to compare the perioperative outcomes of robotic versus laparoscopic complete mesocolic excision (CME) and to assess the safety and feasibility of robotic CME (R-CME) for right-sided colon cancer. As part of this analysis, the feasibility and safety of the robotic approach were also evaluated.

Mucinous adenocarcinoma (MAC) is typically admixed with other pathological components, including conventional adenocarcinoma, signet ring cell carcinoma, and/or neuroendocrine neoplasms. Specifically, signet ring cell differentiation (MASD) is defined as a signet ring cell component comprising less than 50% of the tumor, and neuroendocrine differentiation (MAND) is defined as a neuroendocrine component constituting less than 30%. Furthermore, MAC admixed with conventional adenocarcinoma was defined as classic mucinous adenocarcinoma (CMAC) in this study. Therefore, the study aimed to investigate the clinicopathologic and prognostic differences between patients with CMAC and those with either MASD or MAND [collectively termed mucous adenocarcinoma mixed with other pathological components (MAM)].

Pelvic anatomy is a complex network of organs that varies between individuals. Understanding the anatomy of individual patients is crucial for precise rectal cancer surgeries. Therefore, developing technology that can allow visualization of anatomy before surgery is necessary. This study aims to develop an auto-segmentation model of pelvic structures using AI technology and to evaluate the accuracy of the model toward preoperative anatomical understanding.

Lateral lymph node dissection (LLND) remains controversial owing to differences in oncological principles between East and West, complex pelvic anatomy and the risk of complications. The aim of this systematic review is to determine the number of cases required to achieve surgical competence in LLND and to evaluate postoperative outcomes across different phases of the learning curve.