Wiedemann-Steiner syndrome (WDSTS) is a rare autosomal dominant neurodevelopmental disorder caused by heterozygous pathogenic variants in . Although several large international cohorts have helped define its broad clinical spectrum, data from underrepresented populations remain limited.

Ischemic heart damage reduces the pumping efficiency of the heart by affecting the left ventricular ejection fraction (LVEF) and causing wall motion abnormality (WMA). In daily clinical practice, these parameters are interpreted by physicians using two dimensional transthoracic echocardiography (2D-TTE). Because 2D TTE reports rely on visual evaluations, they are subject to experience-based limitations and exhibit low reproducibility.

Carotid atherosclerosis (CAS) is a key cause of ischemic stroke that is strongly associated with increased risks of cardiovascular disease and vascular death, hence the urgent need to develop therapeutic strategies targeting carotid atherosclerotic plaques that would reduce the overall risk of cerebrovascular events.

Sepsis-associated encephalopathy is a prevalent complication in the sepsis population, especially in patients in the intensive care unit (ICU). The relationship between the hemoglobin glycation index (HGI) and delirium in sepsis patients in the ICU is not yet clearly established.

Hyperuricemia and gout are common metabolic disorders that show substantial disparities in prevalence and management across different socioeconomic status.

Chemotherapy resistance and relapse in acute myeloid leukemia (AML) are associated with poor prognosis. Bone marrow mesenchymal stem cells (MSCs) show enhanced adipogenic differentiation in AML, which may contribute to chemoresistance; however, the underlying mechanisms remain incompletely understood.

Depression and hearing loss (HL) commonly occur in the aging population and may arise from shared mechanisms.

is globally distributed and highly prevalent in parts of South America, the Mediterranean, Eastern Europe, the Middle East, Africa, China, and Australia. This systematic review explores the epidemiological and clinical features of urogenital system-cystic echinococcosis (UGS-CE).

Low bone mineral density (BMD) is a common age-related condition that elevates the risk of fractures and mortality. Machine learning (ML) techniques offer a promising approach for early prediction using readily available clinical, biochemical, and demographic data.

Thyroid nodules are common in clinical practice, with malignancy detected in about 5% of cases. Current risk-stratification approaches, which rely on sonographic features and cytopathological assessment, have notable limitations, especially for indeterminate nodules categorized as Bethesda III.

Hyperuricemia is associated with poor clinical outcomes in several cardiovascular diseases, including heart failure (HF). However, whether lowering serum uric acid (SUA) levels improves the prognosis of HF remains insufficiently studied.