This study aimed to evaluate the long-term risk of stroke following dementia diagnosis and compare stroke risk across dementia subtypes using nationwide cohort data.

Evaluating formal and informal care utilization in Alzheimer's disease (AD) is crucial for assessing the economic impact of novel disease-modifying treatments. The Resource Utilization in Dementia-Lite (RUD-Lite) scale is widely used to measure care utilization in dementia; however, RUD-Lite data is limited for mild cognitive impairment (MCI) and mostly from observational studies. We analyzed RUD-Lite data from a study of semorinemab (NCT03289143) in MCI (i.e., prodromal AD) and mild AD dementia (i.e., mild AD) to explore potential differences in care utilization between observational and interventional studies.

The aging of family caregivers and the growing number of older adults living alone have intensified concerns about dementia care in Japan. Early and effective assessment of caregiving competence is essential for providing timely support. This study aimed to develop the Caregiving Competence Scale for Dementia (CCSD) for primary family caregivers.

Standard cognitive screening instruments such as the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA) often fail to identify cognitive impairment in individuals with low literacy or no formal education, as these tests rely heavily on reading, writing, and abstract reasoning. In Morocco and other low- and middle-income countries (LMICs), this limitation contributes to the under-recognition and diagnostic inaccuracy of dementia, particularly in communities with limited access to education or healthcare resources.

As a major contributor to dementia burden worldwide, Alzheimer's disease (AD) pathogenesis involves critical phosphorylated tau (p-tau) abnormalities. This research employed bibliometric methods to systematically evaluate worldwide scientific trends, emerging foci, and international collaboration patterns regarding p-tau in AD research.

As global population aging intensifies, falls among older adults have emerged as a critical public health challenge. While evidence indicates Sex differences in fall rates, few Chinese studies have examined sex-specific risk factors. This study aimed to investigate sex disparities and determinants of falls among Chinese adults aged 45 and above using data from the China Health and Retirement Longitudinal Study (CHARLS).

Cognitive decline is a pressing public health concern in older adults. The recently proposed Life's Crucial 9 (LC9) score, which integrates cardiovascular and mental health metrics, may offer a novel framework for predicting cognitive impairment.

High plasma homocysteine (Hcy) is a well-established risk factor for cardiovascular disease and stroke, but its role in cognitive impairment (CogI) remains unclear. This study investigated the relationship between plasma Hcy levels and CogI in middle-aged and elderly Chinese adults.

Despite less education being common in Latin America, there is no systematic review on the use of brief cognitive screening (BCS) tools in illiterate and low-educated adults in the region. We systematically reviewed brief cognitive tests used to identify dementia in illiterate or low-educated adults from South America (SA).

Mild cognitive impairment (MCI) and mild dementia are critical stages at which non-pharmacological strategies may help delay further cognitive decline. While multimodal interventions show short-term benefits, evidence on long-term cognitive trajectories, particularly regarding adherence, remains limited. We examined 5-year changes in cognitive function among individuals with MCI or mild dementia participating in a multimodal day-care program, focusing on adherence levels.

We aimed to explore the performance of the Kimberley Indigenous Cognitive Assessment - Cognitive component (KICA-Cog) and the Clock Drawing Test (CDT) in older Aboriginal and Torres Strait Islander adults with dementia and without dementia in the Let's CHAT Dementia study.

This study aimed to comprehensively assess the impact of caregiver, environmental, and individual factors on agitation symptoms in patients with Alzheimer's disease (AD) and identify key modifiable factors.

Cognitive impairment represents a prevalent issue among patients undergoing hemodialysis (HD). Nevertheless, the majority of existing studies have predominantly focused on its influencing factors from a single-dimensional perspective. This study aimed to comprehensively investigate the multifaceted factors contributing to cognitive impairment in patients undergoing HD by applying the health ecological model.

Memory impairment in Parkinson's disease (PD) is characterized mainly by impaired recall with preserved recognition. Despite its clinical importance, there are only a limited number of simple bedside memory tests that can assess both recall and recognition memory together, and that can also be used to detect the neuroanatomical changes in PD. To address this issue, we examined whether a simple memory test that can evaluate both recall and recognition memory can detect cortical abnormalities related to memory impairment in PD.

Falls are a critical public health issue, with executive function (EF) impairment being a contributing factor. However, whether apolipoprotein E4 (ApoE4) influences the relationship between EF and falls is unclear. This study investigated the potential moderating effect of ApoE4 on the EF and falls relationship in older adults with unimpaired cognition, mild cognitive impairment (MCI), and Alzheimer's disease (AD) dementia.

When the phenomenal rise of artificial intelligence (AI) with super-human capabilities is juxtaposed against the relentless decline of a person with dementia, it lends the impression that AI is more human than the person with progressive dementia. However, to accord a higher standing to AI intuits a limited appreciation of what it means to be human. This article explicates how confronting the present day realities of AI and dementia can remind us of the foundations of being human and inspire better care for those living with dementia.

This article aimed to analyze the association between subjective memory complaints (SMCs) and cognitive performance in elderly indigenous individuals of the Xukuru do Ororubá ethnicity in Brazil.

Progranulin (PGRN), a secreted glycoprotein, plays a crucial role in several biological processes. However, its association with cognitive impairment in patients with coronary artery disease (CAD) remains unclear. This study aimed to evaluate the relationship between serum PGRN levels and cognitive impairment in patients with CAD.

We aimed to report the prevalence of mild cognitive impairment (MCI) among healthcare-seeking Indian older adults and study the relationship between serum leptin and adiponectin with MCI.

Conventional non-pharmacological interventions for dementia and mild cognitive impairment (MCI) often face challenges related to motivation and adherence. Esports may offer a more intrinsically motivating alternative, but the evidence base remains limited. We aimed to map the existing evidence on esports interventions in individuals with clinically diagnosed dementia or MCI.

Cognitive function is key to aging and independence. Our aim was to evaluate the associations of domain-specific cognitive performance with disability and frailty. Understanding these associations can improve clinical decision-making and patient outcomes in aging populations.