Ventricular tachycardia (VT) is a life-threatening arrhythmia frequently observed in structural heart diseases, including LMNA-related cardiomyopathy, a genetic disorder associated with high risk of sudden cardiac death and progressive systolic dysfunction. While catheter ablation is an established therapeutic option for VT, its efficacy in cardiac laminopathy remains poorly defined.

Cardiac resynchronization therapy (CRT) is an established treatment for advanced heart failure, but approximately 30% of patients fail to respond. This study aimed to develop and evaluate deep learning models using preimplantation electrocardiogram (ECG) data to predict CRT response.

There is limited data on long-term safety and efficacy of subcutaneous implantable cardioverter defibrillator (S-ICD) in Asian patients with a lower body mass index (BMI) due to smaller body build.

Same-day discharge (SDD) after catheter ablation for atrial fibrillation (AF) may improve patient satisfaction and optimize healthcare resources. Pulsed field ablation (PFA) offers a favorable safety profile, potentially enabling broader adoption of SDD strategies.

Safe and effective left atrial (LA) access is a critical step in catheter ablation procedures. While radiofrequency wire (RFW)-based transseptal puncture (TSP) offers advantages over mechanical needle (MN) techniques, adoption in Europe has been limited due to concerns about the need for costly adjunctive imaging. This study evaluated the feasibility of using RFW-based TSP within fluoroscopy-only pulsed field ablation (PFA) procedures.

The domesticated pig (Sus scrofa domesticus) is widely used as a large animal model in cardiovascular research due to its anatomical and physiological similarities of its heart to the human heart, particularly concerning coronary circulation. However, notable differences in action potential shape, electrical activation pattern, as well as ion channel composition between porcine and human hearts limit translatability.

Titanium hypersensitivity is an uncommon but important challenge in patients requiring cardiac implantable electronic devices (CIEDs). Reactions are difficult to predict, often mimic infection, and complicate timely diagnosis.

Cardiac resynchronization therapy (CRT) improves clinical outcomes in patients with heart failure with reduced ejection fraction (HFrEF). However, data on its efficacy in patients with sarcoidosis and HFrEF are limited.

In patients with recurrent atrial fibrillation (AF) despite durable pulmonary vein isolation (PVI), the optimal catheter ablation (CA) strategy remains unclear. Non-pulmonary vein (non-PV) foci contribute to AF recurrence, whereas the benefit of empirical posterior wall isolation (PWI) is inconsistent.

High density electroanatomical mapping (EAM) is the standard for identifying functional substrate in scar-related ventricular tachycardia (VT), but it is limited by its two-dimensional nature and increased procedural complexity. Imaging-based strategies provide anatomical characterization but lack functional information. We evaluated a novel digital twin model (CardioMat) to non-invasively predict functional substrate in three-dimensions.

Proper stroke and bleeding risk assessment is an essential part of clinical decision-making in patients with atrial fibrillation (AF). This study aims to determine whether the dynamic assessment of CHADS-VASc and HAS-BLED scores over time enhances stroke and bleeding risk prediction.

Cardiac resynchronization therapy (CRT) is a well-established treatment for patients with heart failure (HF). Recently, left bundle branch area pacing (LBBAP) has emerged as a more physiological alternative to biventricular pacing (BVP) for CRT. This study aimed to evaluate the cost-utility of LBBAP CRT compared with BVP CRT.

Conventional substrate mapping for scar-related ventricular tachycardia (VT) often fails to fully delineate critical arrhythmogenic components. Functional mapping strategies using extrastimuli have shown promise but are limited by procedural complexity.