Patients with active vitiligo are treated with systemic immunosuppressants to halt disease progression. However, clinical features associated with patients whose condition is more difficult to control are unknown.

In many Western countries, access to a dermatologist can be difficult, while the incidence of skin cancer has risen steadily over the past 50 years.

Mucous membrane pemphigoid (MMP) is a rare autoimmune bullous dermatosis which predominantly affects the mucous membranes and, occasionally, the skin. The exact pathogenesis of MMP remains unclear and should be considered as a unique phenomenon, which involves the formation of subepithelial blisters and fibrosis.

Impetigo is a common, highly contagious bacterial skin infection primarily affecting children. Treatment usually involves topical or oral antibiotics, and numerous clinical trials have been published to support these therapeutic approaches.

Acne, a common inflammatory skin disorder, is influenced by factors like hormones, age, and stress. Sleep also affects acne, as poor sleep quality can exacerbate skin issues.

Psoriasis is a chronic systemic inflammatory disease that requires long-term treatment strategies to maintain sustained disease control. Treatment persistence is an important real-world indicator of therapeutic effectiveness and tolerability. Guselkumab, an IL-23 inhibitor, has shown favorable persistence in several studies, but extended long-term data remain limited.

Receiving gifts, especially during the Christmas festivities, is a common experience for healthcare providers. Gift-giving, being a spontaneous expression of gratitude, could enable the assessment of true patient satisfaction.

Patients with mycosis fungoides (MF) have a higher risk of developing second primary malignancy. The type of second malignancy varies across the studies, and no established guidelines currently exist for screening MF patients.

Prurigo nodularis (PN) management remains a significant challenge due to its chronicity, treatment resistance, and scarcity of approved treatments and to its impact on patients' quality of life.

Atopic dermatitis (AD) is a chronic inflammatory skin condition characterized by pruritic, dry, eczematous lesions. Traditionally regarded primarily as a cutaneous disorder influenced by genetic and environmental factors, AD is increasingly recognized as a multisystem condition involving immune, microbial, and neuroendocrine interactions.

Randomized controlled trials have suggested that tretinoin, a topical retinoid, can improve wrinkling in photodamaged skin; however, its overall effectiveness remains subject of debate.

Dimethyl fumarate (DMF) is an approved conventional systemic treatment for psoriasis that does not exhibit any drug-drug interactions or cumulative organ toxicities.

Acne vulgaris, affecting around 9.4% of the global population, is a common disorder of the pilosebaceous unit. Approximately 95% of affected individuals develop some degree of scarring, which, along with active acne, contributes significantly to psychosocial morbidity.