Heart failure is a complex, progressive and life-limiting condition that affects individuals beyond physical symptoms. Psychosocial and behavioural symptoms, such as anxiety, depression, cognitive impairment, and social withdrawal, substantially impact their quality of life. Despite increasing recognition of multidimensional symptom burden across heart failure trajectory, these non-physical symptoms are often under-recognised by clinicians and researchers. This review summarises current contemporary evidence on symptom experiences from diagnosis of heart failure through to end-of-life, highlighting key features along this continuum.

Adolescents and young adults (AYAs) with cancer are a vulnerable population affected by disparities in survivorship care access. These disparities are pronounced in low- and middle-income countries (LMICs) but exist even within high-income settings, affecting vulnerable and underserved groups. This expert review explores disparities in fertility preservation, psychosocial health, nutritional care, cardiovascular health, and secondary malignancies of AYA survivorship.

Social isolation and loneliness are common in people with advanced illness. This leads to reduced quality of life and all-cause mortality. The aim of this review is to identify the causes of social isolation in those with serious illness and consider the role of Public Health Palliative Care (PHPC) and Compassionate Communities in reducing these insidious issues.

Accurately predicting survival in metastatic breast cancer (MBC) is essential to support personalized treatment decisions. This scoping review examines the current applications of artificial intelligence (AI) models for survival prediction in MBC and highlights their relevance in improving clinical outcomes.

This review seeks to explain the impact of cultural and spiritual factors on end-of-life care decision-making from different countries to assist in the development of coherent responses for palliative care.

This systematic review aims to evaluate how the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Brain Cancer (EORTC QLQ-BN20) and Functional Assessment of Cancer Therapy-Brain (FACT-Br) are used in prospective brain tumor studies in the past decade, particularly in assessing quality of life (QoL). It aims to assess variability in QoL outcomes across treatment types, use of supplemental tools, and assessment of data completeness and concordance with cognitive assessments.

Low- and middle-income countries (LMICs) bear over half of the global cancer mortality but have access to only 5% of global radiotherapy resources. As the cancer burden rises and equity in palliative care gains global attention, a focused review on palliative radiotherapy access in LMICs is both timely and necessary.

The primary aim of this review was to identify and describe the tools or methods used to capture patient-reported experiences and outcomes related to palliative care provided within acute hospital settings.

Bereavement support in care homes is a critical aspect of end-of-life care that has gained increasing attention in recent years. The purpose of this rapid mixed-methods review is to synthesise evidence on pre- and post-bereavement support interventions as well as facilitators and barriers of bereavement for care home staff, residents, and bereaved family members in care homes.

To highlight promising pre-clinical work seeking to target cancer-associated tissue/muscle wasting.

The initiation/continuation of clinically assisted hydration (CAH) in patients with advanced cancer, especially those in the last days of life, remains highly controversial. The purpose of this article is to review recent developments relating to this medical intervention.

Time spent in nature has been shown to reduce chronic pain symptoms. However, individuals living with high impact chronic pain often face substantial accessibility barriers to nature. Recent advances in immersive virtual reality (VR) provide opportunities to deliver restorative nature-based experiences directly to patients. This review provides key insight to recent advances into nature-based analgesic mechanisms alongside the role of VR in improving access to the therapeutic benefits of nature.

Neuropathic pain affects especially older persons and this review aims at discussing neuropathic pain prevalence, evaluation and treatment and how to optimize management. Older persons are prone to develop neuropathic pain essentially because aging is associated with an increased incidence of comorbidities, immune dysfunction, higher prevalence of herpes zoster infections, higher occurrence of diabetes, surgical interventions and of central nervous system pathologies.

The aim of this review is to discuss the relationship between cachexia in lung cancer and the role of supportive and palliative care.

Four commonly used quality of life (QoL) questionnaires for patients with hepatobiliary cancers are the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Liver Module (QLQ-LMC21), the Quality of Life Questionnaire Hepatocellular Carcinoma-Specific Module (QLQ-HCC18), the Quality of Life Questionnaire Biliary Tract Cancer and Gallbladder Cancer Module (QLQ-BIL21), and the Functional Assessment of Cancer Therapy-Hepatobiliary (FACT-Hep). The objective of this systematic review is to compare the characteristics and psychometric properties of these four QoL instruments.

Musculoskeletal pain following a road traffic crash is common and incurs substantial personal and economic costs. Current recommended treatments of reassurance and advice to stay active, exercise and simple analgesics are not very effective. This review describes the current evidence for health outcomes and potential processes involved in the persistence of pain. It also outlines promising current and future treatments aimed at the prevention of chronic pain after musculoskeletal injury.

This review aims to provide a comprehensive, multidisciplinary perspective on recent advancements and future directions in spinal cord stimulation (SCS) for chronic pain management. It emphasizes the evolving science of patient selection, technological innovations, cost-effectiveness considerations, and future direction of SCS in pain medicine.

Nutritional care is consistently overlooked in oncology practice. It is a critical factor everyone acknowledges, but few actively address, leaving patients neglected. This article explores the challenges of ensuring optimal nutritional care in oncology.