Iron-based phosphate binders (IBPBs) are used for the treatment of hyperphosphatemia. However, the erythropoiesis effects of IBPB treatment in peritoneal dialysis (PD) patients have not been fully investigated.

Post-transplant diabetes mellitus (PTDM) presents a growing global health challenge. Limited understanding of PTDM in Asians needs to be explored.

Oxidative stress (OS), inflammation, and lipoprotein dysfunction contribute to the high cardiovascular disease (CVD) risk in chronic kidney disease (CKD) patients undergoing hemodialysis (HD). This study examined whether OS-related biomarkers-myeloperoxidase (MPO), paraoxonase-1 (PON1), and homocysteine (HCY)-and their derived ratios (MPO/PON1, MPO/HDL-C, PON1/HDL-C) are associated with cardiovascular risk.

To date, despite the new lipid-lowering drugs, some subjects do not reach LDL-cholesterol and/or lipoprotein(a) [Lp(a)] goals and lipoprotein apheresis (LA) plays a role in atherosclerosis prevention.

Patients with end-stage kidney disease require renal replacement therapy (RRT); however, little is known about the treatment in patients who return to RRT after graft loss.

Regional citrate anticoagulation (RCA) has gained increasing attention as a superior anticoagulation strategy in pediatric continuous renal replacement therapy (CRRT). Compared to systemic heparin anticoagulation (SHA), RCA offers significant advantages, including prolonged circuit lifespan, reduced clotting rates, and a lower incidence of bleeding complications. While heparin remains widely used due to its availability and ease of administration, its systemic effects, particularly the risk of bleeding and heparin-induced thrombocytopenia, pose considerable challenges in critically ill children. Studies have consistently demonstrated that RCA reduces transfusion requirements and enhances circuit survival without increasing bleeding risk. Despite potential metabolic concerns such as citrate accumulation, metabolic alkalosis, and electrolyte imbalances, these risks can be effectively managed with careful monitoring and protocol adjustments. As pediatric CRRT protocols continue to evolve, RCA is emerging as the preferred first-line anticoagulation method, particularly in patients with high bleeding risk. The growing body of evidence supports its wider clinical application, promising better treatment outcomes and improved survival rates in critically ill pediatric patients requiring CRRT.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to significant morbidity and mortality worldwide, with acute kidney injury (AKI) emerging as a significant non-pulmonary complication of COVID-19. This study aimed to evaluate the effect of hemodialysis (HD) membrane type on the outcomes of COVID-19 patients with AKI requiring dialysis.

This study investigated inflammatory markers involved in the pathogenesis of atherosclerosis in patients with Chronic Kidney Disease (CKD) undergoing maintenance hemodialysis (HD).

Lipoprotein apheresis reduces low-density lipoprotein (LDL) cholesterol in high-risk patients, but its effects on plasma ion levels remain unclear. The objective of this study was to systematically evaluate the impact of apheresis on plasma calcium, sodium, potassium, magnesium, and chloride concentrations.

This pioneering study aimed to examine the effects of virtual reality (VR)-based videos on symptoms, vital signs, and comfort levels in hemodialysis patients, offering an innovative approach to improving their quality of life.

Sepsis is a life-threatening clinical syndrome, and renal impairment associated with sepsis significantly increases patient mortality. Blood purification techniques are crucial in managing sepsis by removing inflammatory mediators and toxic substances from the bloodstream, thereby improving outcomes. Traditional modalities, including continuous renal replacement therapy, hemodialysis, and hemoperfusion, have demonstrated clinical efficacy in this context. Recent advancements in blood purification filters have enhanced sepsis treatment strategies. This review assesses the mechanisms and clinical applications of novel filters such as the oXiris filter, AN69ST membrane, CytoSorb, Hemopurifier, and others, focusing on their effectiveness in eliminating toxins and inflammatory mediators. The oXiris filter has demonstrated superior capacity to remove small molecular toxins, pro-inflammatory cytokines, and endotoxins while promoting renal protection and enhancing microcirculation. In contrast, the AN69ST membrane and CytoSorb filters have shown promising efficacy in cytokine clearance, though their ability to remove endotoxins is limited. The Hemopurifier specifically targets endotoxins like lipopolysaccharides, effectively suppressing inflammatory responses and mitigating renal damage. Furthermore, the integration of Extracorporeal Carbon Dioxide Removal (ECCO2R) with continuous renal replacement therapy (CRRT) offers benefits, including the regulation of carbon dioxide levels, maintenance of acid-base balance, and enhanced clearance of inflammatory factors from circulation. Additionally, selective removal of lipopolysaccharides (LPS) can alleviate leukopenia and immune dysregulation, preserving renal function. This review aims to provide clinical guidance for optimizing individualized treatment protocols to enhance survival rates and improve the quality of life for patients with sepsis-related AKI. Incorporating these advanced filtration technologies into routine clinical practice can transform sepsis management and pave the way for innovative therapeutic strategies in critical care.

This review systematically summarizes the current status of cognitive frailty in maintenance hemodialysis patients, including its prevalence, assessment and diagnostic criteria, associated risk factors, and the clinical application status and progress of related risk prediction models both domestically and internationally. The analysis aims to provide methodological references for future development and implementation of cognitive frailty risk prediction models tailored to this specific patient population.

This study investigated the value of procalcitonin in the diagnosis of Gram-negative (G-) bacterial peritonitis associated with peritoneal dialysis.

Therapeutic plasmapheresis (TP) is an extracorporeal treatment method used for a variety of patients with various diseases.