Buprenorphine-based treatments outcomes in pregnant opioid-dependent women: A systematic review and meta-analysis
Opioid addiction poses a significant challenge to both the health of mothers and the outcomes for their newborns. Treatments based on buprenorphine offer a proven strategy for addressing opioid dependence among pregnant women. Various studies have examined the effectiveness of buprenorphine treatments versus methadone, revealing several potential advantages of buprenorphine for the outcomes of newborns. This systematic review sought to clarify the benefits and risks associated with buprenorphine therapy.
Estimating community-level prevalence of opioid use disorder: Extrapolating from Medicaid claims data and other publicly available data sources in Ohio, USA
Addressing the opioid crisis requires opioid use disorder (OUD) prevalence estimates at the community level for targeted interventions. This study presents a new method that utilizes Medicaid claims data and publicly available data to estimate OUD prevalence at the United States (US) county level and compares it with other existing estimates.
The impact of opioid, cannabis and cocaine use disorder on the risk of diabetic retinopathy in patients with type 2 diabetes mellitus
Opioid use disorder (OUD), cannabis use disorder (CUD) and cocaine use disorder have been associated with a range of adverse health outcomes, including certain ocular manifestations; however, their impact on diabetic retinopathy (DR) remains insufficiently explored. This study aimed to measure the association between OUD, CUD and cocaine use disorder and the risk of DR among patients with type 2 diabetes mellitus (T2DM).
Substance Use and Sex Index version 2 (SUSI-2): Validation of a brief questionnaire for the measurement of behaviours associated with transmission of blood borne viruses and sexually transmitted infections
This study sought to validate a community-acceptable Substance Use & Sex Index (SUSI) for use in substance use intervention research. SUSI aims to measure behaviours associated with the transmission of blood-borne viruses (BBV) and sexually transmitted infections (STI) among people who use substances and incorporate contemporary sexual and drug practices.
Associations between county-level e-cigarette-inclusive Tobacco 21 law population coverage and e-cigarette use behaviors among United States adolescents in Monitoring the Future
In the United States (US), Tobacco 21 (T21) laws set the minimum legal sale age for all tobacco products to 21 years. This study aimed to examine whether e-cigarette-inclusive T21 laws were associated with e-cigarette use behaviors and related disparities among US adolescents.
Cannabis consumption in Australia 2018-2025: Socio-economic and regional trends from wastewater and survey data
This study examined whether socio-economic status (SES) and geographic remoteness are associated with cannabis consumption across Australia by comparing wastewater-based surveillance (WBS) data and self-reported cannabis use in national household surveys.
How the sales of oral nicotine pouches correlate with prices and respond to taxes on cigarettes and e-cigarettes
BACKGROUND AND AIMS: Oral nicotine pouches (ONPs) have seen a dramatic rise in sales since their introduction to the US market in 2016. We aimed to define the relationship between ONP prices and sales (e.g. price elasticity of demand) and determine how taxes on cigarettes and e-cigarettes (ECs) impact ONP sales.
Changes in clinical features and severity in patients presenting to European emergency departments with acute cannabis toxicity over the 10-year period from 2013 to 2022
In recent years, the potency of natural cannabis products (herb and resin) has increased with a higher delta- 9-tetrahydrocannabinol (Δ9-THC) content, but there are limited data on trends on clinical presentation and severity of toxicity in cannabis users consulting the emergency department (ED) for acute intoxication. This study aimed to analyse the evolution over time of clinical findings and severity of presentations in a large series of patients presenting to European EDs with acute toxicity after lone cannabis use.
Social cognition in Korsakoff's syndrome: A meta-analysis
Korsakoff's syndrome is an alcohol-related neurocognitive disorder characterized by episodic memory impairments, apathy, confabulations and poor illness-insight. This meta-analysis aimed to estimate mean effect sizes of performance in social cognition in people with Korsakoff's syndrome (KS) compared with controls.
Examining changes in the prevalence of cost-motivated alcohol reduction attempts in the context of a cost-of-living crisis and alcohol duty reforms: A population survey of risky drinkers in Great Britain, 2021-2024
Affordability of alcohol is a key driver of consumption. The cost-of-living crisis in Great Britain has been putting pressure on household budgets since late 2021. In addition, the UK Government implemented substantial reforms to the alcohol duty system and increased alcohol taxes in 2023. This study aimed to estimate changes in the monthly prevalence of cost-motivated alcohol reduction attempts among risky drinkers over this period.
Drug use among people in prison: A global review of epidemiology, harms and interventions
People who use drugs are overrepresented in the criminal justice system. We aimed to provide a broad synthesis of the epidemiology, harms and interventions related to drug use and drug use disorders among incarcerated adults worldwide, and highlight gaps in evidence and practice.
Outdated tools, underestimated harm: Modernizing cannabis surveillance in a post-legalization era
Canada's 2018 legalization of non-medical cannabis was positioned as a public health initiative, intended to shift cannabis use from criminalization to regulation. Since then, cannabis access and consumption have grown significantly but the systems used to monitor cannabis-related harms have not kept pace. Most national surveys remain focused on patterns of use rather than indicators of harm. Cannabis use disorder (CUD), a clinical condition with well-established diagnostic criteria, remains rarely measured, often misclassified, and largely absent from policy discussions.
Differences in benefits of office based opioid treatment: Secondary analyses across sub-groups in the PROUD randomized controlled implementation trial
Female, Hispanic, and Black patients with opioid use disorder (OUD) are less likely to receive OUD medication treatment than other patients. The PROUD (PRimary care Opioid Use Disorders treatment) trial demonstrated that implementation of primary care (PC) nurse care management increases OUD medication treatment compared with usual care (UC). This study assessed whether the PROUD intervention's effect differed across sex, race and ethnicity.
Has alcohol consumption in England returned to pre-COVID-19 pandemic levels? A monthly population study, 2014 to 2024
To determine whether alcohol consumption in England had returned to pre-pandemic levels by December 2024, after the initial rise in 2020 across the total population and subgroups.
Motivational smoking cessation counselling and community-based follow-up after hospitalisation for vascular disease: A randomised controlled trial
Evidence for motivational interviewing for smoking cessation is weak, with limited data on long-term abstinence rates. This trial aimed to evaluate the effect of in-hospital motivational interviewing-based smoking cessation counselling combined with proactive referral to community-based follow-up on 6- and 12-month continuous smoking abstinence in patients with atherosclerotic vascular disease.
Changes in wastewater measures of alcohol consumption in Alice Springs, Australia, 1 year after the introduction of restrictions on alcohol sales
To evaluate changes in community consumption and wholesales of alcohol before and after alcohol restrictions were implemented in 2023, aimed at reducing alcohol-related crime and violence.
Heated tobacco product use and tobacco abstinence: A prospective cohort study
Heated tobacco products (HTPs) are increasingly used by individuals attempting to quit smoking, particularly in Japan where HTP use is prevalent; however, the effectiveness of HTPs in achieving complete tobacco abstinence remains unclear. This study aimed to estimate the likelihood of complete tobacco abstinence and combustible cigarette abstinence among exclusive HTP users and dual users compared with exclusive combustible cigarette users.
Telemedicine-assisted buprenorphine induction versus standard of care: A randomized controlled non-inferiority trial
Although buprenorphine-based opioid agonist maintenance treatment (OAMT) is effective, logistical, economic and stigma-related barriers limit access. Telemedicine-Assisted Buprenorphine Induction (TABI) may address these barriers. This study evaluated the non-inferiority of TABI compared with the Standard of Care (SoC) for buprenorphine induction.
Repeated-dose behavioral intervention to reduce opioid overdose among overdose survivors with opioid use disorder: A two-site phase III randomized controlled trial
The emergence of fentanyl in the street market for opioids has limited the benefits of some interventions to manage opioid overdose; thus, preventing the occurrence of opioid overdose is essential. We tested a behavioral intervention shown to prevent heroin overdose in a pilot study, in two United States cities with prevalent fentanyl.
The association between family environment and food addiction in children and adolescents: A prospective cohort study
Food addiction is a dysfunctional chronic psychological disease. Family environment, a modifiable factor, has demonstrated considerable contribution to food addiction. Our objective was to analyze the relationship between family environment and food addiction.
Contingency management interventions for substance use and addictive behaviours: Review of the United Kingdom evidence base
Substance use and other addictive behaviours including gambling remain major public health concerns in the UK. Despite the effectiveness of substance use treatment approaches, treatment adherence and success rates remain low. Contingency Management (CM), a behavioural intervention using positive reinforcement, is a promising approach to enhance clinical outcomes; however, its implementation in UK settings remains limited. This scoping review aimed to explore how CM has been adopted to improve outcomes for substance use and addictive behaviours in the UK, addressing the gap between international evidence and UK-specific healthcare needs.
The effect of anodal transcranial direct current stimulation on affective impulsivity in methamphetamine users: A randomized experimental study
Methamphetamine use disorder (MUD) is associated with significant impairments in impulsivity control, contributing to relapse and poor treatment outcomes. Transcranial direct current stimulation (tDCS) over the left dorsolateral prefrontal cortex (DLPFC) may be helpful in modulating these symptoms. This study aimed at [1] investigating the differential effects of anodal and cathodal tDCS on craving, affective impulsivity, and motor impulsivity; and [2] exploring the correlations between changes in affective impulsivity & drug craving, and alterations in resting-state electroencephalography (Rs-EEG) microstate parameters following tDCS interventions.
Efficacy of cognitive behavioral therapy-based smartphone app for smoking cessation in China: A randomized controlled trial
Smoking is the leading preventable cause of premature death in China, yet less than 10% of smokers seeking to quit receive treatment. This study aimed to test the efficacy of a cognitive behavioral therapy (CBT)-based smoking cessation intervention ('Smokefree Life') via a smartphone app in China.
Alcohol approach-avoidance task behavior and brain potentials differentially predict ecologically assessed alcohol craving and consumption in early emerging adulthood
The current study measured the extent to which different neurobehavioral indices of incentive-motivational salience attribution to alcohol cues predict alcohol craving and consumption in the natural environment.
Trends and correlates of current use of illicitly traded tobacco in Australia: Evidence from a decade of national surveys
Tobacco taxes reduce smoking, particularly among low socioeconomic groups; however, some individuals seek cheaper alternatives instead of quitting. This study estimated use of illicitly traded tobacco among Australian adults who smoke and examined associations with sociodemographic, smoking-related (including quit intentions and attempts) and other illicit substance use factors.
Can a participant-referred 'study buddy' increase retention of rural people who use drugs in research? A multi-site, randomized trial
To test the efficacy of a participant-referred "study buddy" intervention compared with standard retention strategies in retaining rural people who use drugs (PWUD) in longitudinal research.
