One-carbon metabolism (OCM) nutrients are essential for methylation processes and may be involved in the pathogenesis of rheumatoid arthritis (RA), but prospective evidence remains limited. This study aimed to investigate the association between dietary OCM nutrients and RA risk, and their interactions with genetic and lifestyle factors.

To reduce the risk of recurrent cardiovascular events in patients with established cardiovascular disease (CVD), guidelines recommend adopting a more plant-based diet. The EAT-Lancet diet, which focuses on plant-based foods, is associated with a lower risk of CVD in apparently healthy people. However, the relationship in patients with established CVD is unclear. Therefore, the aim of this research was to quantify the relationship between the EAT-Lancet Healthy Reference Diet (HRD) and risk of recurrent CVD in patients with established CVD.

Although recent studies suggest associations between temporal meal patterns, diet quality, and health outcomes such as obesity and cardiometabolic risk, the evidence remains inconclusive, highlighting the need for further investigation. This study aimed to evaluate meal patterns, including meal frequency, breakfast skipping and timing of energy intake (late or early), and their associations with diet quality and body mass index.

A growing body of evidence suggests diets rich in flavonoids may protect against metabolic-dysfunction associated steatotic liver disease (MASLD) development and progression. As the gut microbiome is important in the biotransformation of flavonoids to their constituent bioactive metabolites, studies on the potential mediating role of the gut microbiome in the association between dietary flavonoid intakes and MASLD are warranted but lacking. Thus, this study aims to examine the associations between a diet rich in flavonoids and MASLD, and assess the potential mediating role of the gut microbiome.

to evaluate the effects of three interventions (conventional yogurt; probiotic yogurt, and isolated probiotic) on bone and heart parameters in a chronic kidney disease (CKD) model.

Consumption of seaweed products has become increasingly popular in certain consumer segments, but the high iodine content of some of these products is of concern. We aimed to 1) assess the amount of iodine present in a selection of seaweed products; 2) determine iodine bio-accessibility from these products; and 3) estimate the daily intake of iodine from seaweed-containing products by Dutch consumers.

We considered the secondary effects of medically tailored groceries high in fibre or healthy fats on sodium and potassium intakes.

Improving human and planetary health is one of the most important challenges of the current century. Demand-side food policy strategies can be implemented to achieve this dual objective. To develop and implement policy measures effectively, it is essential to conduct upfront analyses that demonstrate their potential impact.

Maternal nutrition during pregnancy is key for offspring neurodevelopment. Given the role of glucose in brain function, assessing carbohydrate quantity and quality, including glycemic index (GI), glycemic load (GL) and carbohydrate quality index (CQI), may provide insights into early brain development. This study examined the associations between maternal dietary carbohydrate intake and neurodevelopmental outcomes in early childhood.

Dietary fibers differ in their molecular structure, which influences their breakdown under digestive conditions. This study investigates how fiber molecular structure affects resistance to digestion using in vitro models.

A ketogenic diet (KD), high in fat and low in carbohydrates, induces ketosis characterized by elevated circulating ketone bodies. While both KD and ketone bodies have demonstrated therapeutic potential in various pathophysiological conditions, their effect on inflammatory bowel diseases remains controversial. This study aimed to investigate the impact of a KD and ketone ester (KE), an ingestible form of ketone bodies, on intestinal inflammation.

The Paleolithic Diet Fraction (PDF) estimates the proportion of absolute dietary intake derived from food groups included in the Paleolithic diet. In the Malmö Diet and Cancer Study (MDCS), higher PDF and lower systemic low-grade chronic inflammation (SLGCI) have been associated with lower cardiometabolic morbidity and mortality. We examined associations between PDF and SLGCI in the MDCS.

Legumes are promoted as climate-friendly and healthy protein sources. This study evaluated the association between replacing red and processed meat, poultry, or fish with equal amounts of legumes and the risk of gallbladder disease.

Interest in plant-based protein in the UK is increasing due to health, environmental, and ethical considerations. Recent studies have explored how different protein sources impact satiety and related gut hormone responses, with evidence suggesting varied responses between animal-based and plant-based proteins. Skewed protein intake patterns, especially at breakfast, present an opportunity for improving dietary protein distribution in populations who may require increased protein intake but often face appetite reductions. This study determined the acute effect of consuming a plant-based, high protein drink containing 30 g of protein (HPDp); an animal-based, high protein breakfast containing 30 g of protein (HPBa); and a low-protein (10 g), high-carbohydrate breakfast (HCLPB) on satiety hormone responses, subjective appetite and subsequent energy intake in older and younger populations when consumed at breakfast. Eighteen heathy adults completed this within-subject, counterbalanced, cross-over study, (12 under 35 years of age and six over 65 years of age). Measurements for appetite were obtained at baseline, 30, 60, 90, 120, 150, 180, 210 and 240 min, and plasma, GLP-1 and PYY at baseline, 30, 60, 90, 120, 180 min post breakfast consumption. No difference in appetitive responses was found between the HPDp and the energy- and protein-matched HPBa, with both eliciting greater GLP-1 and PYY (both p < 0.004) responses compared with a high carbohydrate, low protein meal. Subjective appetite was also suppressed to a greater extent with HPDp compared with HCLPB (p = 0.001). No differences were observed in ad libitum energy intake.

This study aimed to establish trends in overweight and obesity prevalence among adults living in Ireland (18-64 years) and older adults (> 65 years) over three decades, from 1990 to 2024.

In the UK, more than half of the food supply is composed of ultra-processed foods (UPF). However, the association between UPF intake and osteoporosis risk remains unclear. This study aimed to investigate this association and explore potential mediating biomarkers.

Odd-chain saturated fatty acids (SFAs) have shown potential metabolic benefits, may exert protective metabolic effects. However, their association with MetS and the potential role of insulin resistance remains unclear.

Plate-clearing behavior (PCB), a maladaptive behavior in a food environment characterized by large, energy-dense portions of food, may contribute to weight gain over time. If a portion size is selected that causes overeating, a trade-off exists between food waste and weight gain due to PCB. However, patterns between PCBs and pre-meal portion planning to prevent overeating (PPP-O) remain overlooked. This study aimed to identify these patterns in various meal situations and describe the demographic, anthropometric, psychological, and lifestyle-related characteristics of those following each pattern.