Ascending aorta (AscAo) dilatation assessment and definition in pediatric bicuspid aortic valve (BAV) is challenging. We compared the Pediatric Heart Network (PHN) nomogram against the Halifax (HZ) one and analyzed their association with body surface area indexing (BSAI).

Fluoropyrimidines can cause angina-like chest pain, often attributed to coronary vasospasm. We retrospectively reviewed 137 patients at Cleveland Clinic (2017-2023) who developed chest pain during 5-fluorouracil or capecitabine treatments. Most events occurred early (75 % within four cycles). Troponin elevation (42 %) and ischemic electrocardiographic changes (43 %) were common, yet most catheterized patients had no obstructive coronary disease. Rechallenge was attempted in 64 % of patients, with recurrence in 36 %, and no predictors of recurrence were identified. Fluoropyrimidine-associated angina is therefore frequent, with high rates of recurrence, and unpredictable, highlighting the need for standardized diagnostic and management strategies.

Heart failure (HF) patients who exhibit improvement in systolic function following atrial fibrillation (AF) ablation may experience better outcomes than those who do not. However, the prognostic significance of such improvement compared to originally preserved systolic function remains unclear.

Physical frailty is a prognostic determinant in heart failure (HF) patients, but its association with the modes of death remains unclear. We investigated the associations between walking status and modes of death in patients with HF with preserved ejection fraction (HFpEF) and those with non-HFpEF.

An enlarged v-wave amplitude and a large v-wave in the pulmonary artery wedge pressure (PAWP) suggest impaired left atrial (LA) reservoir function. This study investigated the clinical importance of enlargement of v-wave amplitude in patients with wild-type transthyretin amyloid cardiomyopathy (ATTRwt-CM).

Cognitive dysfunction is prevalent in patients with heart failure (HF) and predicts poor prognosis. The Six-Item Screener is a brief tool that requires no materials and can be administered easily in a variety of care settings. We evaluated whether this tool detects cognitive dysfunction and predicts all-cause mortality in older HF patients, in comparison with the Mini-Cog.

Transthyretin-related amyloid cardiomyopathy (ATTR-CM) results from mutations in the TTR gene (vATTR) or conformational changes in wild-type TTR protein (wtATTR). The aim of this study was to characterize the specificities of cardiac involvement in patients with TTR V30M mutation.

Whether the pre-hospital 12-lead electrocardiogram transmission (ph12ET) protocol is more effective than the pre-hospital ambulance notification protocol (phAN) for managing patients with acute myocardial infarction (AMI) is unclear.

Left ventricular ejection fraction (LVEF) serves as a prognostic marker in heart failure (HF) patients, and screening for undiagnosed HF and meticulous monitoring are crucial for improving outcomes in HF patients. The novel contactless camera-based photoplethysmography (PPG), measured by FHVitals SDK (FaceHeart Corp., Taipei, Taiwan), is the first remote PPG (rPPG) method approved by the U.S. Food and Drug Administration (FDA) for measuring heart rate and respiratory rate. A clinical study also demonstrated the accuracy in detecting atrial fibrillation. The aim of this study was to evaluate the accuracy of rPPG in identification of HF with LVEF <50 %.

Sarcoidosis, a multisystem granulomatous disease, can affect any organ and has various clinical presentations. Patients with sarcoidosis with cardiac involvement have a poorer prognosis than those without cardiac involvement. The prognostic value of the clinical manifestations at the time of cardiac sarcoidosis (CS) diagnosis remains unknown.