Chinese Journal of Integrative Medicine

Nature's Remedies: Future of Allergic Rhinitis Prevention through Natural Products?
Zhu LJ, Zhao ZZ, Cai YJ, Mao J, Ge SA and Jiang L
Resveratrol Attenuates Inflammation in Acute Lung Injury through ROS-Triggered TXNIP/NLRP3 Pathway
Huang WH, Fan KY, Sheng YT and Cai WR
To evaluate the protective effects of resveratrol against acute lung injury (ALI) and investigate the potential mechanisms underlying the reactive oxygen species (ROS)-triggered thioredoxin-interacting protein (TXNIP)/NOD-, LRR- and pyrin domain-containing protein 3 (NLRP3) pathway.
Wenyang Lishui Formula Ameliorates Symptoms of Ovarian Hyperstimulation Syndrome: A Prospective Cohort Study
Xin XY, Wang Y, Zhang H, Zhang JC, Fan MJ, Zhang X, Xu J, Ye Y, Hao XY, Li D and Li R
To study the clinical efficacy of Wenyang Lishui Formula (WYLSF) in preventing ovarian hyperstimulation syndrome (OHSS) and explore the suitable range of estradiol (E) on the human chorionic gonadotropin (HCG) day in patients with OHSS using WYLSF.
Inhibitory Effects of Nardostachys Jatamansi DC. Volatile Oil on Psychological Factors SP/CORT-Induced Hyperpigmentation
Yang M, Cheng K, Gu J, Wu HL and Li YM
To explore the inhibitory effects of Nardostachys Jatamansi DC. volatile oil (NJVO) on psychological factors substance P (SP)/cortisol (CORT)-induced hyperpigmentation.
A Review on 10 Traditional Medicinal Plants from Radix Group and Their Application in Skincare and Skin-Related Ailments
Das G, Chen TV, Duc DPN, Triet NT, Ai NXM, Rodriguez-Torres MDP, Pal K, Shin HS and Patra JK
Shogaol: A Natural Treasure from Ginger with Promising Therapeutic Applications
Sankaran S, Vellingiri A, Varghese SM, Venu AK, Shetty A, Mahadev M, Dubey A, Thiruvengadam R, Venkidasamy B, Kondapavuluri BK and Thiruvengadam M
Puerarin Regulates Gut Homeostasis in T2DM Rats Involving Structural and Functional Alterations of Gut Microbiota and Paneth Cell Function
Wu YZ, Wang L, Sun YX, Yang WW, Wei X, Tao Q, Liang Q, Min HY and Gao Q
To investigate the impact of puerarin on gut microbiota and epithelial integrity and glucose metabolism on a type 2 diabetes mellitus (T2DM) rat model.
Anti-inflammatory and Anti-apoptotic Effects of Hypericum Japonicum and its Active Compounds in Hepatic Fibrosis
He YJ, Yang CM, Liu XD, Miao LQ and Wang LH
To explore the therapeutic efficacy of Hypericum japonicum (HJ) and its active compounds in mitigating hepatic fibrosis by elucidating their anti-inflammatory and anti-apoptotic effects.
Effect and Mechanism of Cerebrovasodilation Induced by Total Flavonoids of Chuzhou Chrysanthemum in Rats
Wang X, Wu M, Li YW, Zhang XY, Cheng YF, Wen JY, Chen S and Chen ZW
To investigate cerebral vasorelaxation of total flavonoids of Chuzhou chrysanthemum (TFCC) in rats and its mechanism.
Tongxinluo Adjunctive Therapy and 12-Month Cardiovascular Outcomes after ST-Segment Elevation Myocardial Infarction: A Real-World Multicenter Prospective Cohort Study
Yuan GQ, Chang CC, Yang LM, Yang LB, Xiao MT, Wei XX, Kang XX and Sun YH
To evaluate the efficacy and safety of Tongxinluo in improving medium- and long-term prognosis of patients with ST-segment elevation myocardial infarction (STEMI) in a real-world setting.
Polysaccharide of Danggui Buxue Decoction Attenuates Colorectal Cancer via Modulating Intestinal Microflora and Metabolites
Guo M, Zhang XC, Guo DF, Wei SX, Cao JN, Li XD and Liu DW
To explore whether polysaccharide of Danggui Buxue Decoction (formula polysaccharide, FP) could attenuate colorectal cancer (CRC) via modulating intestinal microflora and metabolites.
Prevention and Treatment of Doxorubicin and Trastuzumab-Induced Cardiotoxicity with Compound Danshen Dripping Pill
Yu NX, Lin MM, Xu J, Cao B, Yang JH, Li RS, Li GH and Li CY
To elucidate the therapeutic effect and mechanism of Compound Danshen Dripping Pill (CDDP) on cardiotoxicity caused by doxorubicin (DOX) and trastuzumab (TRZ) METHODS: Eighteen Sprague-Dawley (SD) rats were randomly divided into the normal group (normal saline), the model group (DOX/TRZ), and CDDP administration group (DOX/TRZ+CDDP), by a random number table, with 6 rats in each group. Rats' were administered either DOX or saline via tail vein injection 6 times over an 11-day period. One week later, they received either TRZ or saline via intraperitoneal injection 6 times over another 11-day period. All rats received CDDP or saline via oral gavage continuously for 36 days. Then, echocardiography was performed on the rats, and biochemical parameters of blood and heart samples were determined. Rats' feces were taken for intestinal flora testing and plasma metabolites were analyzed using untargeted metabolomics.
Risk Factors for Severity of Adverse Events Associated with Xuebijing Injection: A Propensity Score-Matched Analysis
Zheng R, Chen Z, Zhong XY, Chen Z, Wang PQ, Cui HR and Shang HC
To determine risk factors associated with the severity of Xuebijing Injection (XBJ)-related adverse events (AEs).
Honeysuckle-Derived Exosome-Like Nanovesicles Alleviate Cisplatin-Induced Acute Kidney Injury by Anti-Inflammation and Mitochondrial Function Protection
Gong WC, Li JX, Hu XJ, Huang YL, Wu AL, Li YS, Wang XQ, Zhang XX, Mou XZ and Yang XH
To explore the potential of honeysuckle-derived exosome-like nanovesicles (HELNVs) for preventing cisplatin-induced acute kidney injury (AKI).
Four Isosteroidal Alkaloids from Fritillaria Alleviate Lipopolysaccharide-Induced Inflammation in vitro and in vivo through MyD88- and TRIF-Dependent Signaling Pathways
Aga EB, Pai MX, Zhang MR, Tse WM, Tse KWG, Luo YF and Ye BG
To investigate the anti-inflammatory effects and mechanisms of action of 4 steroidal alkaloids (ebeiedinone, imperialine, chuanbeinone, and peimisine) in Fritillaria.
Effect and Safety of Phytosomal Curcumin Supplementation on Migraine Patients: A Randomized, Double-Blind and Placebo-Controlled Trial
Shojaei M, Khorvash F, Sahebkar A, Sathyapalan T and Bagherniya M
To investigate the effect and safety of phytosomal curcumin supplementation on patients with migraine.
Isoquercitrin Improves Insulin Resistance by Inhibiting PTP1B-Regulated IRS/PI3K/AKT Signaling Pathway
Liu SY, Yu LJ, Zhang SN, Yue JK, Jiang GJ, Lu SH, Li YJ, Meng JY and Huang GH
To explore the molecular mechanism by which protein tyrosine phosphatase 1B (PTP1B) enzyme regulates insulin resistance (IR) in diabetes mellitus, and the regulation of isoquercitrin (IS) on PTP1B in vitro and in vivo.
Suanzaoren Decoction Alleviates Anxiety- and Depression-Like Behaviors Induced by Chronic Restraint Stress via Regulating Pyramidal Neuron Activity in Basolateral Amygdala of Mice
Chen CF, Gao YH, Fang Q, Zhou YF, Liu Y, Wu J, Chen H, Wang LC and Chen L
To elucidate the modulation mechanism of Suanzaoren Decoction (SZRD) on basolateral amygdala (BLA) neuronal activity to alleviate chronic restraint stress (CRS)-related behavioral deficits.
Salvianolic Acid B Exerts Antiphotoaging Effect on Ultraviolet B-Irradiated Human Keratinocytes by Alleviating Oxidative Stress via SIRT1 Protein
Zhang QJ, Luo X, Zheng YW, Zheng JQ, Wu XY, Wang SM and Shi J
To explore the anti-photoaging properties of salvianolic acid B (Sal B).
Sanren Decoction Ameliorates Metabolic Dysfunction-Associated Steatotic Liver Disease by Protecting Mitochondrial Function
Yin YX, Hu YY, Wang JJ, Tang H, Fang Y, Jiang X, Feng Q, Zhao Y, Xin X and Peng JH
To evaluate the effects of Sanren Decoction (SRD) on metabolic dysfunction-associated steatotic liver disease (MASLD) induced by high-fat diet (HFD) based on the protective effect of hepatocyte mitochondrial function.
Cardioprotective Effect and Mechanism of Panaxadiol Saponin Component in Radiation-Induced Heart Disease in Mice
Lan JJ, Gai JY, Song WJ, Liu Y, Zhao YN, Wang BL, Lyu KR, Gao RL and Yu XL
To investigate the effect and mechanism of panaxadiol saponin component (PDS-C) in radiation-induced cardiac injury (RIHD).