Validation of the French version of the Meaning of Life Questionnaire (MLQ) in patients admitted for crisis hospitalization in a psychiatric emergency service (crisis center)
The interpersonal theory of suicide emphasizes the importance of a sense of belonging and hypothesizes that finding meaning in life reduces suicidal behavior. The Meaning of Life Questionnaire (MLQ) is widely used internationally to assess this relationship to meaning. Despite its popularity, it lacks a validated French version, limiting its application in French-speaking populations. This absence hinders research on meaning in life and suicide prevention in these populations.
Harnessing exercise for brain health: BDNF, neuroplasticity & well-being
Physical activity is increasingly recognized not only for its physical benefits but also for its profound impact on brain health. We reviewed the effects of exercise on mood and cognition with a particular focus on the underlying biological mechanisms, notably brain-derived neurotrophic factor (BDNF) and neuroplasticity. Emerging evidence indicated that exercise, particularly aerobic activity, elevates BDNF levels in key brain regions such as the hippocampus, fostering neurogenesis and synaptogenesis. These processes contribute to improved emotional regulation, alleviating symptoms of depression and anxiety, while also enhancing cognitive functions such as memory and attention. Furthermore, we investigated the implications of these findings across diverse age cohorts, including children, adults, and older adults, to elucidate age-specific effects on neurobiological processes such as growth, survival, differentiation, and neurogenesis. We also propose future research directions to enhance understanding of these mechanisms, with a particular emphasis on the therapeutic potential of physical activity as a broadly accessible intervention for promoting mental health and cognitive function across the lifespan.
Update and adaptation of the body satisfaction and global self-perception questionnaire (BSGSPQ)
The body satisfaction and global self-perception questionnaire could be related to questionnaires measuring well-being. The first objective of this work was to complete the validation of the body satisfaction and global self-perception questionnaire by searching for underlying concepts using principal component analysis. The second was to validate the questionnaire externally, by studying correlations with several other questionnaires.
Odor Hedonic Profile (OHP): A sensitive tool in depressive populations
The aim of the present study was to assess the Odor Hedonic Profile (OHP) to evaluate its sensitivity in relation to the level of depression.
Sexual orientation, coming out and suicidal ideation in young French LGBP people
Young individuals identifying as lesbian, gay, bisexual, or pansexual (LGBP) are particularly vulnerable to suicidal ideation (SI). This study examines the relationships between sexual orientation, gender, coming out, and suicidal ideation among young French LGBP adults. The sample included 459 participants aged 18 to 35, 50.1% (n=230) of them identifying as LGBP. Data were collected through an online survey using the French version of the Suicidal Ideation Attributes Scale (SIDAS-FR). Findings revealed significantly higher levels of suicidal ideation among LGBP individuals compared to heterosexual people, with bisexual individuals reporting the highest levels. Women of sexual minorities, particularly those who are bisexual and pansexual, were identified as the most vulnerable subgroup for SI. Men of sexual minorities also reported increased SI compared to heterosexual men. Coming out emerged as a protective factor, with participants who had disclosed their sexual orientation to both parents reporting a lower level of SI. The study highlights the need for targeted interventions to support LGBP individuals, focusing on reducing stigma, promoting family acceptance, and strengthening community-based mental health resources.
Decision of compulsory psychiatric hospitalization in patients referred to emergency departments for a first forensic expertise: Impact of the pre-existing care network
The recourse to compulsory psychiatric hospitalizations is authorized in Belgium in case of the presence of strict legal criteria defined by the law on the protection of patients with mental illness. In recent years, the number of compulsory psychiatric hospitalizations has been constantly increasing, leading to an increasing saturation of specialized hospitalization units. To better understand this problem, the aim of this study was therefore to investigate the impact of a medical contact during the three months preceding the occurrence of a first forensic expertise on the decision to involuntarily hospitalize psychiatric patients referred to emergency departments.
[Towards an integrative understanding of complex trauma]
The body of knowledge on trauma is rapidly expanding. Since 2022, the WHO has been calling for the history of adversity to be systematically taken into account when assessing the state of health of all individuals. But at this stage, our understanding of the precise mechanisms of complex trauma remains incomplete. In fact, its pathophysiology lies at the crossroads of neurobiological, psychological and relational fields of study. The aim of this review is to set out the key elements of this scientific literature in order to move towards a more global and comprehensive vision, which remains a challenge. The clinical forms of complex trauma are analyzed in the light of the neurobiology of chronic and early stress, cognitive-emotional disorders, and relational and attachment imbalances. Four dimensions each play a major role in the psycho-traumatic equation: characteristics relating to adversity factors, circumstances of onset, any prior vulnerabilities, and environmental resources (particularly relational support). Borderline personality disorder appears to be one of the faces of complex trauma, and a valuable model for understanding a pathophysiology that takes place in two stages, in which previous psychobiological changes contribute to the disproportionate or unrelated appearance of symptoms in relation to current environmental factors. This pathophysiology of a profound link between early experiences, alterations in the self and affective regulation disorders in adolescence or adulthood, raises new questions about the definition and understanding of psychiatric disorders, and first and foremost personality disorders, which are at the crossroads of the shift from "simple" trauma to complex trauma. Understanding the mechanics of trauma ultimately involves a shift from a symptom-centered approach to a dual approach involving the symptom in a synchronic (instantaneous) perspective and the patient's history in a diachronic (temporal evolution) perspective. It is also a shift from the subject to his or her environment, which calls for a global and systemic vision.
Cannabis use and male sexuality in a Tunisian sample: A case-control study
Cannabis is widely used for various reasons, including its effects on sexuality. It has significant short- and long-term health consequences. However, its impact on sexual health remains uncertain. This study assesses sexual function in Tunisian cannabis users compared to non-users.
[Speech markers as objective indicators of apathy: New insights from a case study]
Apathy, commonly observed in neurocognitive disorders, is characterized by a reduction in goal-directed behavior with a reduction of initiatives interests and emotions. This article presents the case of Mrs. B., a 70-year-old patient with mild neurocognitive disorder and apathy, who underwent an intervention combining transcranial direct current stimulation (tDCS) and cognitive training delivered through a web application.
The pathologies of artificial intelligence: Lessons for and from clinical psychiatry
Lifetime suicide attempts among Moroccan psychiatrists: Prevalence, methods and risk factors
Studies have shown that psychiatrists have a higher suicide rate compared to the general population and other medical specialists.
[Behavioral problems in child protection: Understanding and intervening from the concept of complex trauma]
Adolescents supported by child protection services (CPS) represent a population exposed to repeated relational trauma that significantly increases the risk of developing complex trauma characterized by polymorphic symptomatology. The behavioral problems presented by adolescents followed by CPS may fit within this nosographic framework. They can lead to major difficulties in adapting to their environment, especially when the trajectory of polyvictimization is pronounced. Unfortunately, the failure of professionals to recognize this diagnosis remains frequent. As a result, institutional responses are often poorly adapted to the needs of the adolescents concerned, promoting an excessive psychiatrisation of their behavioral manifestations at the expense of a comprehensive and holistic approach rooted in their traumatic history.
[Adversity, adolescent psychiatric disorders and complex trauma: Comorbidities or overlap?]
In a context of debates on the place of complex trauma within psychiatric pathology, it is essential to accurately measure the extent of the effects of adversity across different disorders. Such studies are rare, however, because they often focus on a single diagnosis. The measurement of adversity is usually self-reported, retrospective, and usually includes a single dimension. Furthermore, at-risk family interactions and maltreatment constitute two distinct and central risk factors for both complex trauma and psychiatric disorders. Yet they are rarely studied together, nor through an overview of psychiatric disorders. This is the aim of this study, which hypothesizes that adversity is widely distributed across all the psychiatric disorders of adolescents admitted to psychiatric hospitals, and postulates that it is possible to discern distinct adversity profiles depending on the diagnosis.
[Complex trauma: A theoretical and clinical approach]
The concept of complex trauma (or developmental trauma) has been proposed to refer both to chronic exposure to interpersonal experiences in children and adolescents and to the constellation of possible sequelae that cause significant difficulties throughout life. The purpose of this chapter is to provide an overview of the theoretical and clinical approaches to complex trauma in order to better understand the scope of this concept. Through a review of the literature, this chapter outlines the historical evolution of this concept, its current definition, the diagnostic issues involved, and the preferred directions for its future use in research and clinical practice. This article highlights the significant shift that has taken place over time, from a concept closely linked to the traumatic experiences of individuals and the clinical challenges they face, to a collective responsibility to implement social actions that can lead to deeper structural and systemic change.
[The universitarisation of regions for psychiatric care - Facilitating access to care, combating medical desertification]
Mental disorders are on the increase, while access to care is becoming increasingly difficult for those affected. This article presents the "Projet de Liaison Universitaire de TerritOire du Nord" (PLUTON), an initiative to improve access to psychiatric care in an area of the Hauts-de-France region and to combat medical desertification. Initially conceived as a response to a health crisis, PLUTON has gradually evolved to rethink the organisation of psychiatric care in a given area. The aim was to preserve the structure of sector-based care while adding a university dimension to clinical, research and teaching activities. The success of this project is the result of an innovative, collaborative approach based on the pooling of existing resources. This tried and tested methodology means that the project can be easily and effectively replicated in other areas.
Cognitive therapies and insight in early schizophrenia: A systematic review
This systematic review aims to evaluate the impact of cognitive-behavioral and metacognitive therapies on cognitive and clinical insight into early schizophrenia disease.
[Overview of therapeutic approaches for complex psychotrauma in children and adolescents]
Complex post-traumatic stress disorder (C-PTSD), caused by repeated traumatic events of interpersonal origin (such as physical or sexual violence, or war), leads to severe disorders of emotional regulation, self-perception and interpersonal relationships. Without early diagnosis and intervention, children and adolescents with C-PTSD are at risk of developing chronic mental disorders. Rapid therapeutic interventions are thus required in order to avoid the persistence of symptoms and at-risk behaviours altering the development and life trajectory of these young people. The aim of this article is to provide a state-of-the-art overview of existing therapeutic interventions aimed at professionals who screen, diagnose or care for children or adolescents with C-PTSD. The specific clinical and treatment profiles of these patients (e.g., stabilization, trauma treatment, promoting cognitive and psychological integration processes, self-compassion and engagement in interpersonal relations, family involvement) are detailed, in order to propose a diagnostic strategy and set out the various possibilities for comprehensive management based on adaptations of existing therapeutic protocols for these paediatric populations. Therapeutic, psychological and psychopharmacological approaches that are either validated or in development are presented, along with their current level of scientific evidence. This article highlights the importance of training French-speaking child and adolescent psychiatric professionals in these therapies, and of further developing research in this field.
Body image dissatisfaction in brazilian nutrition students: A cross-sectional study
Body Dysmorphic Disorder (BDD) is a condition characterized by a distorted perception of one's own body image. Individuals with BDD exhibit excessive concern about their appearance, often fixating on perceived flaws that are either imaginary or minor. The prevalence of body image-related eating disorders has been increasing among university students, particularly in health-related fields, where students frequently experience pressure to maintain an ideal body shape and weight.
[Impact of transcranial magnetic stimulation on depressive symptoms relief in patients with chronic neuropathic pain and comorbid depression: A narrative literature review]
Neuropathic pain results from an injury or a dysfunction of the somatosensory system. Management of this disease is complex due to a restricted therapeutic arsenal and limited efficacy of currently available treatments. Because of its chronic and disabling nature, neuropathic pain is strongly associated with depressive disorders. New neuromodulatory approaches such as repetitive transcranial magnetic stimulation (rTMS) represent an innovative therapeutic option with documented efficacy in the treatment of neuropathic pain and major depressive disorder respectively. Despite the frequent comorbidity between neuropathic pain and depressive disorder, there is no accurate data in the literature concerning the place of rTMS in the combined treatment of these two diseases. This narrative literature review was conducted to assess the impact of antalgic rTMS protocols on the improvement of depressive symptoms in patients with chronic neuropathic pain. An analysis of 20 trials showed that motor cortex rTMS protocols with optimised parameters (frequency of at least 10 Hz, at least 2000 pulses per session and at least 10 stimulation sessions) could improve depressive symptoms in patients with chronic neuropathic pain. Other cortical target protocols including dorsolateral prefrontal cortex, anterior cingulate cortex and secondary somatosensory cortex did not seem to be effective in relieving depressive symptoms in these patients. Available data indicates a strong heterogeneity and must be confirmed by large sample size randomized trials.
