Acute nerve injury (ANI) leads to significant neuropathic pain and functional impairment. Current treatments, including nonsteroidal anti-inflammatory drugs (NSAIDs) like meloxicam, provide symptomatic relief but have limited neuroregenerative effects. Varenicline, a nicotinic acetylcholine receptor (nAChR) agonist, has demonstrated neuroprotective and anti-inflammatory properties.

To analyze the spectrum of ocular injuries caused by pressure cooker explosions, evaluate visual outcomes, and highlight the need for increased safety awareness.

Atypical femoral fractures are associated with high rates of non-union and reoperation due to their complex pathogenesis. There is no consensus in literature on the optimal treatment strategy of these difficult cases. This study demonstrates a standardized management protocol for atypical femoral fracture non-unions, with surgical mechanical alignment of the non-union, without bone grafting or use of biological adjuncts, and with immediate unrestricted weight bearing post operatively. The study aimed to examine whether comparable union and complications rates can be achieved to those published in literature.

Musculoskeletal soft tissue injuries (MSKIs) impose a significant burden on the United States (US) healthcare system, constituting a large proportion of emergency department (ED) visits. Understanding the epidemiology of these injuries is critical for identifying at-risk populations, improving preventive measures, and optimizing resource allocation. This study aims to identify and describe trends in MSKIs presenting to US EDs from 2003 to 2023, using the National Electronic Injury Surveillance System (NEISS).

Traumatically injured patients who are detained by law enforcement have variable disposition possibilities that may be unclear to providers. This creates difficulties in discharge planning, and may contribute to disparities in outpatient care. The objective of this study was to evaluate emergency department (ED) utilization, readmissions, and follow-up for traumatically injured patients discharged to jail compared to those discharged to home.

The global trauma burden disproportionately affects low- and middle-income countries(LMICs), which lack robust emergency medical services(EMS). The Global Prehospital Consortium determined Tier-1 EMS response intervals are a priority for investigation. On-scene response intervals for professional ambulance-driven Tier-2 EMS vary by density of centralized ambulance dispatch sites per population, requiring costly infrastructure to improve response times. Community bystander-driven (Tier-1) systems are less costly with diffuse and non-centrally dispatched responders. Therefore, we hypothesized Tier-1 EMS response intervals to emergencies are not distance-related, due to the inherent diffusion of Tier-1 responders.

Helmets play a critical role in preventing and reducing the severity of head injuries in high-risk sports. Understanding the factors influencing equestrian helmet use and safety perceptions is needed to optimise injury prevention strategies.

As the number of older adults with hip fractures rises, improving strategies to prevent postoperative pneumonia is crucial in this vulnerable population. This study aims to evaluate the effect of implementing the ICOUGH protocol for the prevention of pneumonia on the incidence of postoperative hospital-acquired pneumonia in geriatric hip fracture patients.

Distal femur shaft fractures are typically associated with high-energy trauma. Stress fractures involving the distal femur shaft are extremely limited. Therefore, epidemiological characteristics, diagnostic protocol, optimal management strategies, and prognosis of distal femoral shaft stress fractures (DFSSF) remain poorly understood. This study aims to report clinical experience with 10 cases of DFSSF in South Korean military.

This study aimed to investigate the association between frailty and osteoporosis in middle-aged and older adults, and to evaluate the discriminative value of different frailty assessment tools, including the Groningen Frailty Indicator (GFI), SARC-F questionnaire, and a combined GFI + SARC-F score, in identifying patients at risk for osteoporosis.

This letter evaluates the methodological shortcomings in the FEA research conducted by Ma et al. (2025) that contrasts hook plates with tension-band wiring for patellar fractures. Unresolved concerns consist of: uniform bone material characteristics simplifying biomechanics; static loads neglecting dynamic physiological forces; idealized fracture spaces missing clinical variation; and unverified interfaces exaggerating stability. These gaps may exaggerate the effectiveness of the implant. We suggest personalized modeling, simulations of dynamic loading, and studies on mesh convergence to enhance clinical significance. Tackling these issues would enhance forthcoming evaluations of orthopedic devices based on FEA.

The global rise in obesity presents a complex challenge in trauma care, characterized by the "Obesity Paradox." This study aimed to evaluate the biomechanical protection hypothesis and its influence on initial injury severity and clinical outcome in severely injured patients.

The use of an electromagnetic motorized intramedullary telescopic nail (MITN) simplifies humeral lengthening in patients with significant shortening.

The surgical strategy of displaced intra-articular calcaneal fractures (DIACFs) remains technically challenging. While sinus tarsi approach (STA) is widely applied for DIACFs, increasing concerns regarding the wound-related sequelae drive surgeons to target and advance minimally invasive surgery (MIS). This study aims to introduce a tailored distractor-assisted MIS and compares its medium-term outcomes with conventional STA approach reduction and fixation in patients with Sanders Ⅱ and Ⅲ calcaneus fractures.

Open fractures are associated with soft tissue injury and may require reconstruction via delayed flap coverage. The timing of coverage is critical as prolonged time to coverage is associated with increased risk for wound complications. Few studies have included all lower extremity fractures when analyzing time from definitive fixation to coverage. We analyzed the effect of time to flap coverage from both admission and definitive fixation, on fracture-related infections (FRI) in patients admitted with open fractures of the lower extremity.

In recent years, more studies have focused on the outcome parameter (health-related) Quality of Life (QOL) after a severe injury. Psychological complaints are known to be associated with QOL. However, little is known about long-term QOL. Studies in other fields, have shown that, apart from disease, patients' personality may be associated with (long-term) QOL.

The objective of this study is to compare the clinical outcomes of robot-assisted percutaneous screw fixation with traditional ORIF for treating displaced intra-articular glenoid Ideberg Ia fractures.

Equestrian sports have been found to cause high rates of injuries. In clinical practise after such injuries, polytrauma protocol workups usually include whole-body computed tomography (WBCT), CT of the chest, abdomen and pelvis with intravenous iodine contrast medium, and CT of the cervical spine and brain without contrast. The purpose was to investigate the use of WBCT in equestrian-related accidents, to analyse demographics, mechanism of injury (MOI), therapy and severity of equine-related accidents, radiology, and the use of protecting equipment.

This letter addresses the research conducted by Lin et al. regarding the shock index (SI) as an indicator of compensated shock in normotensive trauma cases. We acknowledge the authors' efforts while highlighting significant limitations: overlooked confounding due to cardioactive drugs, survival bias from omitting early fatalities, influences of prehospital fluid resuscitation, and insufficient age-specific SI thresholds. We additionally challenge transfusion as a surrogate for shock and emphasize the variation in injury mechanisms. Suggestions consist of modifications in pharmacovigilance, incorporation of early mortality statistics, and multi-center confirmations with microcirculatory outcomes.