Sleep and Breathing

A study of the relationship between physical fitness index and sleep quality in Chinese adolescents
Wang Y, Wang J, Wu H and Ma Y
To explore the relationship between Physical Fitness Index and sleep quality in adolescents and to provide a theoretical basis for improving adolescent sleep quality.
Early assessment in bulbar-onset amyotrophic lateral sclerosis detects similar rates of nocturnal desaturation and orthopnoea compared to non-bulbar-onset disease
Luu S, McGuiness OA, Menadue C, Piper AJ, Wong KK, Yee BJ and Gray EL
Pulmonary function measures are commonly used to determine timing of non-invasive ventilation (NIV) initiation in amyotrophic lateral sclerosis (ALS). However, these tests may be difficult to perform and unreliable in those with bulbar disease. We evaluated the rates of orthopnoea and nocturnal desaturation detected using nocturnal pulse oximetry (NPO), two key criteria for NIV initiation, separately in people with bulbar-onset and non-bulbar-onset ALS.
Longitudinal analysis of anthropometric indices and the incidence of obstructive sleep apnea
Wu SC, Yang CD, Lin XJ, Chen ST, Cai JY, Lin L, Lian NF, Cai ZM and Chen LD
This longitudinal study evaluated the predictive value of ten anthropometric indices including Waist Circumference (WC), Hip Circumference (HC), Neck Circumference (NC), Body Mass Index (BMI), Waist-to-Height Ratio (WHtR), Waist-to-Hip Ratio (WHR), A Body Shape Index (ABSI), Body Roundness Index (BRI), Weight-adjusted Waist Index (WWI), and Neck-to-Height Ratio (NHR) for incident obstructive sleep apnea (OSA), aiming to identify optimal clinical predictors.
Associations of sleep, lifestyle, and physiological markers with healthspan termination: a prospective cohort analysis
Sambou ML, Wang Y, Xu F, Yakubu S, Liang S and Dai J
The determinants of chronic diseases are complex, and we demonstrated how lifestyle-related factors interact with physiological factors to influence the risk of healthspan termination (HST).
SAS-CARE-1 study: stroke topography and polysomnography-based respiratory sleep characteristics
Filchenko I, Brill AK, Dekkers MPJ, Baillieul S, Seiler A, Manconi M, Wiest R, Bernasconi C, Schmidt MH and Bassetti CLA
Sleep-disordered breathing (SDB) is a risk factor of ischemic stroke but can also appear "de novo" after the acute brain damage. The link between SDB and stroke topography, which remains controversial, was assessed in this study.
The 12 weeks of regular exercise improves sleep quality and mood states in elderly with cognitive impairment
Lee E, Kwak HB, Lim ST and Park DH
This study aimed to determine how 12 weeks of regular exercise, including eccentric resistance exercise and combined exercise (aerobic + resistance exercise), affects sleep quality and mood in elderly individuals with cognitive impairment.
Utility of Belun Ring platform for the diagnosis of obstructive sleep apnea: a systematic review and meta-analysis
Bhatia O, Madan K, Tiwari P, Mohan A, Hadda V, Suri TM and Mittal S
Level 1 polysomnography (PSG) is considered the gold standard test for diagnosing obstructive sleep apnea (OSA). The Belun Ring platform, a recently FDA-approved wearable device, is a potential alternative to PSG for diagnosing OSA. We conducted this systematic review and meta-analysis to assess the diagnostic accuracy of the Belun Ring Platform compared to PSG in adults.
REM-related obstructive sleep apnea: low AHI-high hypoxemia paradox
Verdi EB and Acıcan T
REM-related obstructive sleep apnea (OSA) presents a paradox where a low apnea-hypopnea index (AHI) may mask significant disease. We compared polysomnography, comorbidities, and oxygenation metrics across OSA phenotypes to determine if AHI-based severity classifications underestimate the nocturnal hypoxemia in REM-related OSA.
Research advances in the association between Irisin and obstructive sleep apnea
Luyao S, Chao W, Lei P and Jinxiang G
Obstructive sleep apnea (OSA) is a common disorder characterized by recurrent upper airway obstruction leading to intermittent hypoxia and sleep fragmentation. It is closely associated with cognitive impairment, various cardiovascular and cerebrovascular diseases, and metabolic syndrome. Irisin is a multifunctional myokine activated via the PGC-1α/FNDC5 pathway during skeletal muscle exercise. It is widely expressed in tissues such as the myocardium and brain, exerting multi-organ protective effects including promoting adipose browning, improving insulin resistance, inhibiting inflammation and oxidative stress, enhancing cognitive function, and providing cardiovascular protection. Given the systemic pathological damage caused by OSA and the broad protective effects of irisin, this review systematically explores their association. It focuses on the relationship between irisin levels and OSA severity, as well as the mechanisms of irisin in OSA-related cognitive impairment and comorbidities, aiming to provide new insights for the precise diagnosis and treatment of OSA.
Impact of comorbid obstructive sleep apnea on sleep efficiency and architecture in patients with periodic limb movements: an exploratory study
Ferreira de Almeida M, Amorim P, Lima JC, Rocha E Melo J, Drummond M and
Periodic limb movements during sleep (PLMS) and obstructive sleep apnea syndrome (OSAS) are common sleep disorders that affect sleep quality. Their combined impact on sleep architecture and overall sleep disruption remains uncertain.
Head-of-bed elevation outcomes on apnea severity nasal resistance in obstructive sleep apnea: a multicenter observational study
Maniaci A, Lentini M, Lechien JR, Iannella G, Casale M, Moffa A, Pelucchi S, Caranti A, Pang KP, Rotenberg B and Vicini C
OSA has been demonstrated to be significantly influenced by body position, and supine one making the disease severity worse. Head-of-bed elevation (HOBE) is advocated as an easily applicable positional therapy, yet its hemodynamic response is incompletely elucidated. This investigation assessed the influence of HOBE on polysomnographic (PSG) parameters and nasal resistance drives and the pattern of upper airway collapse, compared with healthy controls in OSA patients.
Validation of the Dutch sleep-related breathing disorder scale from the pediatric sleep questionnaire: a diagnostic accuracy study using polysomnography
Becking BE, Jonkman REG, Stumpel DJPM, van Merkesteyn JPR and Van den Akker-Van Marle ME
Pediatric sleep-disordered breathing (PSDB) is linked to various coexisting problems, and polysomnography (PSG) is the reference standard for diagnosis. However, limited access in primary care to PSG may hinder diagnosis. This study investigates the validity of the Dutch version of the Pediatric Sleep Questionnaire (PSQ) Sleep-Related Breathing Disorder (SRBD) scale as a screening tool for pediatric sleep-disordered breathing (PSDB), comparing its performance to PSG.
Unraveling the connection between the Mediterranean diet and sleep health: from biological mechanisms to clinical implications
Minari TP and Pisani LP
The Mediterranean diet (Med-Diet) is well known for its protective effects against noncommunicable diseases and overall mortality, thanks to its anti-inflammatory, antioxidant, and neuroprotective properties. Simultaneously, sleep is increasingly recognized as a vital modifiable factor that influences health, affecting both physiological and psychological outcomes. This narrative review summarizes epidemiological evidence on how the Med-Diet impacts sleep duration and quality, examines the biological mechanisms behind these effects, and identifies areas for future research.
Multidimensional sleep health and psychological distress: associations in a Community-Dwelling population
Furihata R, Tateyama Y, Shimamoto T, Nishioka N, Takahashi Y, Yamamoto K, Okada H, Nakayama T and Iwami T
To investigate the association between multidimensional sleep health (MDSH) and psychological distress in Japanese community residents.
Ultrasound shear wave elastography of the sternocleidomastoid muscle in patients with obstructive sleep apnea syndrome
Mermit B and Durmaz F
The aim of this study was to evaluate the elasticity and stiffness of the sternocleidomastoid (SCM) muscle in patients with obstructive sleep apnea syndrome (OSAS) using ultrasound shear wave elastography (SWE), and to investigate the potential relationship between SCM muscle stiffness and the severity of OSAS.
Prevalence and factors associated with short and long sleep duration among community-dwelling persons 40 years and older: longitudinal evidence from rural South Africa, 2015-2022
Pengpid S, Peltzer K and Hajek A
The prevalence and associated factors of short and long sleep duration in people 40 years of age and older have not been examined in longitudinal research in Africa. The purpose of this study was to use 3-wave longitudinal data from South Africa to determine these factors and prevalence, also stratified by sex.
Diagnostic value of wearable and contactless technologies for detecting obstructive sleep apnea: a systematic review and meta-analysis
Hasanain M, Akram A, Kabir A, Javed H, Usman M, Jaffar H, Khan AA, Ali Malik GM, Tabassum M, Faizan M, Anjum MU, Umer M and Surani S
BACKGROUND​: Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder, affecting an estimated 1 billion adults worldwide. This study evaluates the diagnostic accuracy of wearable and contactless sleep technologies as alternatives to Polysomnography (PSG) for the detection of OSA.
Integrating bulk and single-cell RNA sequencing data to dissect genetic links between periodontitis and obstructive sleep apnea
Li C
Periodontitis (PD) and obstructive sleep apnea (OSA) are widespread conditions with profound health consequences. Increasing evidence suggests shared pathophysiological mechanisms between PD and OSA, prompting this study to explore their genetic connections using advanced transcriptomic approaches.
Prevalence and characteristics of pulmonary hypertension in obstructive sleep apnea: a systematic review and meta-analysis
Samieirad S, Amini M, Raji H, Sadeghi FH, Rasti N, Doghaei AD, Milani E, Amiriani A, Akbari A, Sorouri S and Baniasad A
Pulmonary hypertension (PH) is a serious cardiovascular complication that can be associated with obstructive sleep apnea (OSA). We aimed to assess the prevalence and characteristics of PH in OSA patients.
Association between daytime sleepiness and impaired expiratory lung function due to smoking in patients with mild-to-severe OSA: an observational study
Sartori G, Fantin A, Ferrari M and Crisafulli E
There are no studies about daytime sleepiness (DS) in patients with obstructive sleep apnea (OSA) and impaired expiratory lung function (IELF) due to the smoking habit. We aimed to evaluate the association between DS and IELF in patients with OSA and look for possible DS-related factors.
Association between sleep disorders and sarcopenia in older outpatients in Vietnam
Nguyen AT, Nguyen TN, Pham TH, Nguyen TX, Nguyen TTH, Nguyen AL, Tran LV and Vu HTT
Sarcopenia is a risk factor for mortality in older people, and little investigation has been carried out into the potentially modifiable factors, such as sleep disorders, associated with sarcopenia, especially among persons living in low-middle income countries. The study aimed to investigate the association between sleep disturbances and sarcopenia in older outpatients.